Zotemtegrast
Zotemtegrast (LY-4268989; MORF-057) is an orally active integrin α4β7 antagonist. Zotemtegrast is applicable to research related to inflammatory bowel diseases such as ulcerative colitis and Crohn's disease.
For research use only. We do not sell to patients.
- CAS No.: 2640360-52-5
- Formula: C35H43F4N3O4
- Molecular Weight:645.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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α4β7 |
Integrin α4β7 is an adhesion molecule on the surface of lymphocytes that mediates the homing of immune cells to the intestinal mucosa and participates in intestinal inflammation and immune responses.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2640360-52-5
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Molecular Weight 645.73
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Formula C35H43F4N3O4
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SMILES
CC1=C(C(C)=CC(C)=C1)C2=CC([C@H](CC(O)=O)NC([C@@H](N3C=C(C(C(F)(F)F)=CC3=O)CCN(C)C)CC(C)C)=O)=C(C(C)=C2)F
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Synonyms
LY-4268989; MORF-057
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)