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Cat. No.: HY-183178

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Teroxalene

Teroxalene is a piperazine-based Schistosomicide. Teroxalene is used for the research of schistosomiasis.

For research use only. We do not sell to patients.

CAS No.: 14728-33-7
Formula: C₂₈H₄₁ClN₂O
Molecular Weight:457.09

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Teroxalene Chemical Structure

CAS No.: 14728-33-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
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Biological Activity

Description

Teroxalene is a piperazine-based Schistosomicide. Teroxalene is used for the research of schistosomiasis^[1].

IC₅₀ & Target^[1]

Schistosome

All Parasite Isoforms :

In Vivo

Teroxalene (Compound VII) (once daily for 5 days) exhibits schistosomicidal activity, with an ED₅₀ of 93 mg/kg in mice and >400 mg/kg in hamsters^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 14728-33-7
Molecular Weight 457.09
Formula C₂₈H₄₁ClN₂O
SMILES

ClC1=CC(N2CCN(CCCCCCOC3=CC=C(C(C)(CC)C)C=C3)CC2)=CC=C1C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Rosi D, et al. Preparation and schistosomicidal activity of some 4-hydroxymethyl-3-chloroanilines. J Med Chem. 1967 Sep;10(5):877-80. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References

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Teroxalene

All Parasite Isoforms