Eesperamicin A1
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 99674-26-7
- Formula: C59H80N4O22S4
- Molecular Weight:1325.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
1.0 x 10-12M
Compound: Esperamicin A1
|
Cytotoxicity against HCT116 human colon tumor cell line
Cytotoxicity against HCT116 human colon tumor cell line
|
10.1016/0960-894X(95)00163-N |
Chemical Information
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CAS No. 99674-26-7
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Molecular Weight 1325.54
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Formula C59H80N4O22S4
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SMILES
CSSSC/C=C1C2=C(C([C@@H](O[C@@]3([H])C[C@@H]([C@H](O)[C@H](C)O3)OC(C4=C(C=C(OC)C(OC)=C4)NC(C(OC)=C)=O)=O)[C@]\1(C#C/C=C\C#C[C@@H]2O[C@@]5([H])[C@@H]([C@H]([C@H](NO[C@H]6C[C@@H]([C@H](SC)[C@@H](C)O6)O)[C@@H](C)O5)O)O[C@@]7([H])C[C@@H]([C@@H](NC(C)C)CO7)OC)O)=O)NC(OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)