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Cat. No.: HY-163482

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ELQ-596

ELQ-596 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice.

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CAS No.: 3023709-98-7
화학식: C₂₄H₁₇ClF₃NO₃
분자량:459.84

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ELQ-596 Chemical Structure

CAS No.: 3023709-98-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Parasite Isoforms :

In Vitro

ELQ-596 (1 nM-1 μM, 62 h) inhibits growth of B. duncani parasites, with IC₅₀ of 32 nM, reveals slightly cytotoxicity in human cell lines HeLa, HepG2, HEK293, and HCT116, with an average IC₅₀ of 30 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3023709-98-7
분자량 459.84
화학식 C₂₄H₁₇ClF₃NO₃
SMILES

ClC1=CC2=C(NC(C)=C(C3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C3)C2=O)C=C1OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vydyam P, et al., Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413. [Content Brief]

Calculators

몰농도 계산기

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Mass Mass

Concentration Concentration

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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ELQ-596

All Parasite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ELQ-596 Related Classifications

HY-163482 Related Classifications