Enniatin B-13C33
Enniatin B-13C33 is the 13C-labeled Enniatin B (HY-N3806). Enniatin B is a Fusarium mycotoxin that acts as an ionophore to form cation-selective membrane channels, disrupt ion homeostasis and mitochondrial function, inhibit cell proliferation, and induce apoptosis, while modulating ERK, p38 MAPK, and STAT3 signaling pathways. Enniatin B is used in research on atherosclerosis, hypercholesterolemia, cervical cancer, and colon adenocarcinoma.
For research use only. We do not sell to patients.
- Formula: 13C33H57N3O9
- Molecular Weight:672.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[11]|
ERK |
p38 MAPK |
STAT3 |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 917-13-5
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Molecular Weight 672.58
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Formula 13C33H57N3O9
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SMILES
[13CH3][13CH]([13C@](O1)([H])[13C](N([13C@H]([13C](O[13C@@H]([13C](N([13C@]([13CH]([13CH3])[13CH3])([H])[13C](O[13C@H]([13CH]([13CH3])[13CH3])[13C](N([13CH3])[13C@@H]([13CH]([13CH3])[13CH3])[13C]1=O)=O)=O)[13CH3])=O)[13CH]([13CH3])[13CH3])=O)[13CH]([13CH3])[13CH3])[13CH3])=O)[13CH3]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. Prosperini A, et al. A Review of the Mycotoxin Enniatin B. Frontiers in public health. 2017;5:304.
[9]. Ficheux AS, et al. Effects of beauvericin, enniatin b and moniliformin on human dendritic cells and macrophages: an in vitro study. Toxicon : official journal of the International Society on Toxinology. 2013 Sep;71:1-10. [Content Brief]
[10]. Krug I, et al. Transport of enniatin B and enniatin B1 across the blood-brain barrier and hints for neurotoxic effects in cerebral cells. PloS one. 2018;13(5):e0197406. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)