Azidocillin
Based on 1 Customer Validation
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases. Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- Pureza: 97.05%
- No. CAS: 17243-38-8
- Fòrmula: C16H17N5O4S
- Peso molecular:375.40
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
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β-lactam |
Azidocillin (0.004-16.0, >16.0 μg/mL; 24 h) inhibits the growth of most bacteria isolated from human mandibular osteitis, with mean MIC values ranging from 0.005 to 1.2 μg/mL across bacterial genera, and only a small subset of strains exhibiting MIC values above 2.0 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 17243-38-8
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Appearance Solid
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Peso molecular 375.40
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Fòrmula C16H17N5O4S
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Color White to off-white
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SMILES
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](N=[N+]=[N-])C3=CC=CC=C3)=O)N1C2=O)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : ≥ 100 mg/mL (266.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Bystedt H, et al. Concentration of azidocillin, erythromycin, doxycycline and clindamycin in dental alveolar serum after single oral doses. Int J Oral Surg. 1977;6(2):65-74. [Content Brief]
[2]. Ryrfeldt A, et al. Biliary excretion of ampicillin, azidocillin and benzylpenicillin in the rat. Acta Pharmacol Toxicol (Copenh). 1973;33(3):219-28. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6638 mL | 13.3191 mL | 26.6383 mL | 66.5956 mL |
| 5 mM | 0.5328 mL | 2.6638 mL | 5.3277 mL | 13.3191 mL | |
| 10 mM | 0.2664 mL | 1.3319 mL | 2.6638 mL | 6.6596 mL | |
| 15 mM | 0.1776 mL | 0.8879 mL | 1.7759 mL | 4.4397 mL | |
| 20 mM | 0.1332 mL | 0.6660 mL | 1.3319 mL | 3.3298 mL | |
| 25 mM | 0.1066 mL | 0.5328 mL | 1.0655 mL | 2.6638 mL | |
| 30 mM | 0.0888 mL | 0.4440 mL | 0.8879 mL | 2.2199 mL | |
| 40 mM | 0.0666 mL | 0.3330 mL | 0.6660 mL | 1.6649 mL | |
| 50 mM | 0.0533 mL | 0.2664 mL | 0.5328 mL | 1.3319 mL | |
| 60 mM | 0.0444 mL | 0.2220 mL | 0.4440 mL | 1.1099 mL | |
| 80 mM | 0.0333 mL | 0.1665 mL | 0.3330 mL | 0.8324 mL | |
| 100 mM | 0.0266 mL | 0.1332 mL | 0.2664 mL | 0.6660 mL |
Azidocillin Related Classifications
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