FK 409
FK 409 is a NO donor that can penetrate cell membranes. FK 409 has a vasodilatory effect on bovine retinal arteries. FK 409 alleviates acute-phase inflammation, induces HSP, and mitigates liver transplantation injury in a rat model of orthotopic liver transplantation. FK 409 can be used in research on cardiovascular diseases and liver transplant rejection and inflammatory immune system disorders.
For research use only. We do not sell to patients.
- CAS No.: 92454-60-9
- Formula: C8H13N3O4
- Molecular Weight:215.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 92454-60-9
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Molecular Weight 215.21
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Formula C8H13N3O4
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SMILES
CC([N+]([O-])=O)/C(CC)=C/C(C(N)=O)=N/O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Man K, et al. FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway. Ann Surg. 2004 Jul;240(1):159-68. [Content Brief]
[2]. Sugimoto K, et al. [Vasodilatory action of FK 409 on bovine retinal arteries--analysis by a microvessel perfusion system]. Nippon Ganka Gakkai Zasshi. 2002 Jun;106(6):338-42. Japanese. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)