Creatine-d2
Creatine-d2 is the deuterated-labeled Creatine (HY-W010388). Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain.
For research use only. We do not sell to patients.
- Formula: C4H7D2N3O2
- Molecular Weight:133.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 57-00-1
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Molecular Weight 133.15
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Formula C4H7D2N3O2
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SMILES
NC(N(C)C([2H])([2H])C(O)=O)=N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4. [Content Brief]
[2]. Gerber I, et al., Stimulatory effects of creatine on metabolic activity, differentiation and mineralization of primary osteoblast-like cells in monolayer and micromass cell cultures. Eur Cell Mater. 2005 Jul 15;10:8-22. [Content Brief]
[3]. Guidi C, et al., Differential effect of creatine on oxidatively-injured mitochondrial and nuclear DNA. Biochim Biophys Acta. 2008 Jan;1780(1):16-26. [Content Brief]
[4]. Cunha MP, et al., Antidepressant-like effect of creatine in mice involves dopaminergic activation. J Psychopharmacol. 2012 Nov;26(11):1489-501. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Creatine-d2 Related Classifications
HY-W010388S2 Related Classifications
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