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Referencia número: HY-101668

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Sulamserod

Name: Sulamserod
Brand: MedChemExpress
SKU: HY-101668
Price: 1067.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: RS-100302)

Sulamserod is a 5-HT4 receptor antagonist, with antiarrhythmic activities.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 219757-90-1
Fòrmula: C₁₉H₂₈ClN₃O₅S
Peso molecular:445.96

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Sulamserod Chemical Structure

No. CAS: 219757-90-1

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Fluorescent Dye

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Descripciòn

Sulamserod is a 5-HT4 receptor antagonist, with antiarrhythmic activities.

IC₅₀ & Target

5-HT₄ Receptor

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In Vivo

Sulamserod (30 mg/kg) prolongs mean ERP (11568 versus 14667 ms, P,0.01) and wavelength (8.360.9 versus 9.960.8 cm, P,0.01), reduces dispersion of ERP (1565 versus 861 ms, P,0.01), and minimally slows conduction velocity (7264 versus 6765 cm/s, P,0.01) in pigs. Sulamserod produces no ventricular electrophysiological effects. Sulamserod terminates atrial flutter in 6 of 8 animals and atrial fibrillation in 8 of 9 animals and prevents reinduction of sustained tachycardia in all animals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 219757-90-1
Peso molecular 445.96
Fòrmula C₁₉H₂₈ClN₃O₅S
SMILES

CS(=O)(NCCN1CCC(CCC(C2=C3OCCOC3=C(N)C(Cl)=C2)=O)CC1)=O
Synonyms

RS-100302
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Rahme MM, et al. Electrophysiological and antiarrhythmic effects of the atrial selective 5-HT(4) receptor antagonist RS-100302 in experimental atrial flutter and fibrillation. Circulation. 1999 Nov 9;100(19):2010-7. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Sulamserod

Ver todos los productos específicos de isoformas 5-HT Receptor

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