AA-17010
AA-17010 is a Cereblon ligand with an IC50 of 0.20 μM and a Ki of 0.08 μM. AA-17010 serves as an E3 ligase ligand for the synthesis of PROTAC KRAS degraders, such as CW-10201 (HY-189305).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3064305-88-7
- Fòrmula: C19H22N4O4
- Peso molecular:370.40
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
Cereblon 0.20 μM (IC50) |
In Vitro
AA-17010 (~3 h) is a high-affinity Cereblon ligand that binds to CRBN with an IC50 of 0.20 μM and a Ki of 0.08 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 3064305-88-7
-
Peso molecular 370.40
-
Fòrmula C19H22N4O4
-
SMILES
O=C(C(N(C(N(C)C1=C2)=O)C1=CC3=C2C4(CCNCC4)CO3)CC5)NC5=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AA-17010 Related Classifications
HY-189348 Related Classifications
Powered by Bioz