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Referencia número: HY-168471

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AAL-149

AAL-149 is a FTY720 (HY-12005) analog and TRPM7 inhibitor (IC₅₀ = 1.081 μM) with multimodal anti-inflammatory effects and without targeting S1P receptors. AAL-149 can be utilized in anti-inflammatory research.

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No. CAS: 177258-60-5
Fòrmula: C₁₈H₃₁NO₂
Peso molecular:293.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

AAL-149 Chemical Structure

No. CAS: 177258-60-5

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Chemical Information
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Descripciòn

IC₅₀ & Target

TRPM7/ChaK1

1.081 μM (IC₅₀)

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Chemical Information

No. CAS 177258-60-5
Peso molecular 293.44
Fòrmula C₁₈H₃₁NO₂
SMILES

N[C@@](CO)(C)CCC1=CC=C(OCCCCCCC)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Busey GW, et al. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. J Gen Physiol. 2024 Jan 1;156(1):e202313419. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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AAL-149

Ver todos los productos específicos de isoformas TRP Channel

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

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AAL-149 Related Classifications

HY-168471 Related Classifications