Aldoview
AldoView (Compound 3) is an intermediate. AldoView can be labeled with fluorine-18 to synthesize [18F]AldoView. [18F]AldoView is a highly selective aldosterone synthase PET imaging agent. AldoView can be used in imaging studies of primary aldosteronism.
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- No. CAS: 1356479-94-1
- Fòrmula: C15H10F3N3
- Peso molecular:289.26
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Radionuclide-Drug Conjugates (RDCs)
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Actividad biológica
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Aldosterone Synthase |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | IC50 |
10000 nM
Compound: 26
|
Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method
Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method
|
[PMID: 26005536] |
Chemical Information
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No. CAS 1356479-94-1
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Peso molecular 289.26
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Fòrmula C15H10F3N3
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SMILES
FC1=CC(C2=NC3=C(N2C4CC4)C=C(F)C(F)=C3)=CN=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)