AP 24149
AP 24149 is a potent Src-Abl dual inhibitor with IC50 values of 9.1, 3.6 nM for Src and Abl, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 926922-29-4
- Fòrmula: C23H24N5OP
- Peso molecular:417.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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Abl 3.6 nM (IC50) |
Src 9.1 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | IC50 |
168 nM
Compound: 10a
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Cytotoxicity against mouse BA/F3 cells transfected with wild-type Bcr-Abl
Cytotoxicity against mouse BA/F3 cells transfected with wild-type Bcr-Abl
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[PMID: 18691885] |
| K562 | IC50 |
109 nM
Compound: 10a
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Cytotoxicity against human K562 cells transfected with wild-type Bcr-Abl
Cytotoxicity against human K562 cells transfected with wild-type Bcr-Abl
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[PMID: 18691885] |
Chemical Information
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No. CAS 926922-29-4
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Peso molecular 417.44
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Fòrmula C23H24N5OP
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SMILES
O=P(C)(C)C(C=C1)=CC=C1NC2=C3N=CN(/C=C/C4=C(C)C=CC=C4C)C3=NC=N2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AP 24149 Related Classifications
HY-10363 Related Classifications
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