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Referencia número: HY-113273

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Ap5A

(Synonyms: Diadenosine pentaphosphate)

Ap5A (Diadenosine pentaphosphate), a diadenosine polyphosphate, is an adenylate kinase inhibitor with a K_i of 2.5 nM. Ap5A can be used for study of cancer.

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No. CAS: 41708-91-2
Fòrmula: C₂₀H₂₉N₁₀O₂₂P₅
Peso molecular:916.37

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Ap5A Chemical Structure

No. CAS: 41708-91-2

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- IC₅₀ & Target
- Cellular Effect
Chemical Information
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Actividad biológica

Descripciòn

Ap5A (Diadenosine pentaphosphate), a diadenosine polyphosphate, is an adenylate kinase inhibitor with a K_i of 2.5 nM. Ap5A can be used for study of cancer^[1].

IC₅₀ & Target

Human Endogenous Metabolite

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Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>=5 μM Compound: Ap5A	Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increase	[PMID: 16539385]
PC-12	IC₅₀	29 μM Compound: 4	Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis	[PMID: 23751098]

Chemical Information

No. CAS 41708-91-2
Peso molecular 916.37
Fòrmula C₂₀H₂₉N₁₀O₂₂P₅
SMILES

O[C@@H]1[C@H](O)[C@@H](COP(OP(OP(OP(OP(OC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2N3C=NC4=C(N)N=CN=C43)(O)=O)(O)=O)(O)=O)(O)=O)(O)=O)O[C@H]1N5C6=NC=NC(N)=C6N=C5
Synonyms

Diadenosine pentaphosphate
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Bone R, et al. Inhibition of thymidine kinase by P1-(adenosine-5')-P5-(thymidine-5')-pentaphosphate. J Biol Chem. 1986 May 5;261(13):5731-5. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Ap5A

Ver todos los productos específicos de isoformas Endogenous Metabolite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Ap5A Related Classifications

HY-113273 Related Classifications