BMS-952048
BMS-952048 is a positive allosteric modulator of mGluR5 with an EC50 of 10 nM.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1375751-32-8
- Fòrmula: C21H13F2N3O2
- Peso molecular:377.34
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
>3000 nM
Compound: 22; BMS-952048
|
Agonist activity at human mGluR5A transfected in HEK293 cells assessed as induction of calcium release by FLIPR assay
Agonist activity at human mGluR5A transfected in HEK293 cells assessed as induction of calcium release by FLIPR assay
|
[PMID: 27496211] |
| HEK293 | EC50 |
10 nM
Compound: 22; BMS-952048
|
Positive allosteric modulation of human mGluR5A transfected in HEK293 cells assessed as potentiation of L-glutamate-induced calcium release incubated for 10 mins by FLIPR assay
Positive allosteric modulation of human mGluR5A transfected in HEK293 cells assessed as potentiation of L-glutamate-induced calcium release incubated for 10 mins by FLIPR assay
|
[PMID: 27496211] |
Chemical Information
-
No. CAS 1375751-32-8
-
Peso molecular 377.34
-
Fòrmula C21H13F2N3O2
-
SMILES
O=C1O[C@H](C2=CC=C(F)C=C2)[C@@H](C3=CC(C#CC4=NC=CC=C4F)=CN=C3)N1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-952048 Related Classifications
HY-123874 Related Classifications
Powered by Bioz