BVB808
BVB808 (NVP_BVB808) is a selective JAK2 inhibitor with approximately 10-fold selectivity for JAK2 over other JAK family members (such as JAK1, JAK3 or TYK2) in vitro. BVB808 inhibits the activity of JAK2 and reduces the phosphorylation of STAT5, thereby blocking the JAK2-dependent cell proliferation and survival signaling pathways. BVB808 can be used in cancer research.
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- No. CAS: 1414587-22-6
- Fòrmula: C29H33F2N7O
- Peso molecular:533.62
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 1414587-22-6
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Peso molecular 533.62
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Fòrmula C29H33F2N7O
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SMILES
FC(C=C1N2C3=NC(NC4=CC=C(N5C[C@@H](N[C@@H](C5)C)C)C=C4)=NC=C3C=C2)=C(C(F)=C1)CN6CCOCC6
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Synonyms
NVP_BVB808
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BVB808 Related Classifications
HY-120604 Related Classifications
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