Exatecan Intermediate 6
Based on 1 Customer Validation
Exatecan Intermediate 6 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 6 can be used to synthesize Antibody-Drug Conjugates (ADCs).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.45%
- No. CAS: 143655-58-7
- Fòrmula: C13H14FNO2
- Peso molecular:235.26
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas ADC Payloads
MoreVer todos los productos específicos de isoformas Topoisomerase
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Actividad biológica
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Camptothecins |
Exatecan (DX-8951) is a?DNA?topoisomerase?I?inhibitor.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 143655-58-7
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Appearance Solid
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Peso molecular 235.26
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Fòrmula C13H14FNO2
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Color Off-white to light yellow
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SMILES
CC(NC(C=C(F)C(C)=C1CCC2)=C1C2=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 25 mg/mL (106.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2507 mL | 21.2533 mL | 42.5065 mL | 106.2663 mL |
| 5 mM | 0.8501 mL | 4.2507 mL | 8.5013 mL | 21.2533 mL | |
| 10 mM | 0.4251 mL | 2.1253 mL | 4.2507 mL | 10.6266 mL | |
| 15 mM | 0.2834 mL | 1.4169 mL | 2.8338 mL | 7.0844 mL | |
| 20 mM | 0.2125 mL | 1.0627 mL | 2.1253 mL | 5.3133 mL | |
| 25 mM | 0.1700 mL | 0.8501 mL | 1.7003 mL | 4.2507 mL | |
| 30 mM | 0.1417 mL | 0.7084 mL | 1.4169 mL | 3.5422 mL | |
| 40 mM | 0.1063 mL | 0.5313 mL | 1.0627 mL | 2.6567 mL | |
| 50 mM | 0.0850 mL | 0.4251 mL | 0.8501 mL | 2.1253 mL | |
| 60 mM | 0.0708 mL | 0.3542 mL | 0.7084 mL | 1.7711 mL | |
| 80 mM | 0.0531 mL | 0.2657 mL | 0.5313 mL | 1.3283 mL | |
| 100 mM | 0.0425 mL | 0.2125 mL | 0.4251 mL | 1.0627 mL |
Exatecan Intermediate 6 Related Classifications
HY-44369 Related Classifications
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