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Referencia número: HY-146232

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F 13714

(Synonyms: F 14679)

F 13714 (F 14679) is a prototypical 5-HT_1A agonist with a pK_i of 10.23. F 13714 induces large Ca²⁺ responses.

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No. CAS: 208109-38-0
Fòrmula: C₂₁H₂₅ClF₂N₄O
Peso molecular:422.90

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

F 13714 Chemical Structure

No. CAS: 208109-38-0

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Actividad biológica

Descripciòn

F 13714 (F 14679) is a prototypical 5-HT_1A agonist with a pK_i of 10.23. F 13714 induces large Ca²⁺ responses^[1].

IC₅₀ & Target

5-HT_1A Receptor

10.23 (pKi)

5-HT_1B Receptor

5.12 (pIC₅₀)

Ver todos los productos específicos de isoformas 5-HT Receptor :

Chemical Information

No. CAS 208109-38-0
Peso molecular 422.90
Fòrmula C₂₁H₂₅ClF₂N₄O
SMILES

O=C(C1=CC(Cl)=C(F)C=C1)N2CCC(CNCC3=CC=C(C)C(NC)=N3)(F)CC2
Synonyms

F 14679
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307(2):608-14. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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F 13714

Ver todos los productos específicos de isoformas 5-HT Receptor

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Chemical Information

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Referencias

Calculators

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F 13714 Related Classifications

HY-146232 Related Classifications