HBF-0079
HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma.
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- No. CAS: 315702-93-3
- Fòrmula: C12H9N5S
- Peso molecular:255.30
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 10
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Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
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[PMID: 18774291] |
| Huh-7 | CC50 |
1.1 μM
Compound: HBF-0079
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Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
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[PMID: 27793566] |
Chemical Information
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No. CAS 315702-93-3
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Peso molecular 255.30
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Fòrmula C12H9N5S
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SMILES
C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HBF-0079 Related Classifications
HY-18203 Related Classifications
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