HSN748
HSN748 is a Ponatinib (HY-12047) analogue and a multikinase inhibitor. HSN748 has inhibitory activity on FLT3, ABL1, RET, PDGFRα/β, MNK1, MNK2 and other kinases. HSN748 can inhibit the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines and can be used in the study of leukemia.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2409925-53-5
- Fòrmula: C27H24F3N7O
- Peso molecular:519.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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PDGFRα |
PDGFRβ |
MNK1 |
MNK2 |
Chemical Information
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No. CAS 2409925-53-5
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Peso molecular 519.52
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Fòrmula C27H24F3N7O
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SMILES
O=C(C1=CC(C#CC2=CN=C3C=CC=NN23)=CN=C1)NC4=CC=C(CN5CCN(CC5)C)C(C(F)(F)F)=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)