iBFAR2
iBFAR2, a BFAR inhibitor, restores the CD8+ TRM cell subset against solid tumors. iBFAR2 promotes JAK2-STAT1 association and STAT1 phosphorylation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 97.24%
- No. CAS: 353484-02-3
- Fòrmula: C19H15F3N2O2
- Peso molecular:360.33
-
Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
iBFAR2 abolishes USP39 ubiquitination, inhibits the JAK2-USP39 interaction and thus suppresses JAK2 deubiquitination, thereby promoting JAK2-STAT1 association and STAT1 phosphorylation in mouse primary CD8+ T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 353484-02-3
-
Appearance Solid
-
Peso molecular 360.33
-
Fòrmula C19H15F3N2O2
-
Color Light yellow to yellow
-
SMILES
FC(F)(F)C1=CC=CC2=C1NC(C3=CC=C([N+]([O-])=O)C=C3)C4C2C=CC4
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
iBFAR2 Related Classifications
HY-170393 Related Classifications
Powered by Bioz