L-738167
L-738167 is an orally active fibrogen receptor antagonist that prevents the binding of fibrinogen to GP IIb/IIIa. L-738167 can be utilized in thrombus research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 163212-43-9
- Fòrmula: C25H34N6O6S
- Peso molecular:546.64
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
>3 nM
Compound: 5
|
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)
|
[PMID: 9191954] |
| HUVEC | IC50 |
>3 nM
Compound: 5
|
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin
|
[PMID: 9191954] |
| HUVEC | IC50 |
>3 nM
Compound: 5
|
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)
|
[PMID: 9191954] |
Chemical Information
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No. CAS 163212-43-9
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Peso molecular 546.64
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Fòrmula C25H34N6O6S
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SMILES
O=C(O)[C@H](CNC(C1=NN2C(C(N(CCC3CCNCC3)CCC2)=O)=C1)=O)NS(=O)(C4=CC=C(C)C=C4)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)