MS910
MS910 is an efficient and selective MEK1/2 PROTAC degrader. MS910 exhibits effective MEK1/2 degradation ability and anti proliferative activity in various cancer cells, such as HT-29 (MEK1 DC50 = 118 nM, MEK2 DC50 = 55 nM) and SK-MEL-28 (MEK1 DC50 = 94 nM, MEK2 DC50 = 38 nM) cells. MS910 is commonly used in cancer research. (Pink: MEK1/2 Ligand (HY-10254); Blue: CRBN Ligand (HY-W087383); Black: Linker (HY-W022240))
(Pink: MEK1 and MEK2 ligand (HY-10254); Blue: Cereblon ligand (HY-W087383); Black: linker (HY-W022240)).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2756323-28-9
- Fòrmula: C41H48F3IN6O11
- Peso molecular:984.75
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas PROTACs
MoreVer todos los productos específicos de isoformas MEK
More
Actividad biológica
|
MEK1 |
MEK2 |
Cereblon |
Chemical Information
-
No. CAS 2756323-28-9
-
Peso molecular 984.75
-
Fòrmula C41H48F3IN6O11
-
SMILES
O=C(C1=CC=C(C(F)=C1NC2=CC=C(C=C2F)I)F)NOCCCNCCOCCOCCOCCOCCOCCNC3=CC=C4C(N(C5C(NC(CC5)=O)=O)C(C4=C3)=O)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MS910 Related Classifications
HY-170982 Related Classifications
Powered by Bioz