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Referencia número: HY-B2030S

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Propanil-d₅

Name: Propanil-d5
Brand: MedChemExpress
SKU: HY-B2030S
Price: 240.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Propanil-d₅ is the d₅-labeled Propanil (HY-B2030). Propanil is an orally active immunotoxic Herbicide. Propanil causes delayed and sustained loss of CTL lytic function, as well as irreversible impairment of secondary/tertiary CTL responses. Propanil inhibits PHA-induced increases in IL-10, IFN-gamma, IL-2, and intracellular calcium, as well as anti-CD3-induced IL-10 and IFN-gamma release. Propanil induces splenomegaly, thymic atrophy, bone marrow toxicity, and hemoglobin oxidation. Propanil can be used in research on methemoglobinemia and anemia, as well as liver injury.

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No. CAS: 1398065-82-1
Fòrmula: C₉H₄D₅Cl₂NO
Peso molecular:223.11

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (284 KB)

Propanil-d₅ Chemical Structure

No. CAS: 1398065-82-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

IC₅₀ & Target

^[2]^[6]

IL-10

IL-2

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Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

No. CAS 1398065-82-1
Unlabeled CAS 709-98-8
Peso molecular 223.11
Fòrmula C₉H₄D₅Cl₂NO
SMILES

[2H]C([2H])([2H])C([2H])([2H])C(NC1=CC(Cl)=C(C=C1)Cl)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (284 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sheil JM, et al. Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors. Environmental health perspectives. 2006 Jul;114(7):1059-64.

[2]. Corsini E, et al. Immunomodulatory effects of the herbicide propanil on cytokine production in humans: In vivo and in vitro exposure. Toxicology and applied pharmacology. 2007 Jul 15;222(2):202-10.

[3]. McMillan DC, et al. Propanil-induced methemoglobinemia and hemoglobin binding in the rat. Toxicology and applied pharmacology. 1990 Sep 15;105(3):503-7.

[4]. Salazar KD, et al. Evidence for a novel endocrine disruptor: the pesticide propanil requires the ovaries and steroid synthesis to enhance humoral immunity. Toxicological sciences : an official journal of the Society of Toxicology. 2006 Sep;93(1):62-74.

[5]. Xie YC, et al. The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production. Toxicology and applied pharmacology. 1997 Jul;145(1):184-91.

[6]. Zhao W, et al. Propanil affects transcriptional and posttranscriptional regulation of IL-2 expression in activated EL-4 cells. Toxicology and applied pharmacology. 1999 Jan 15;154(2):153-9.

[7]. Hong T, et al. Propanil impairs organ development in zebrafish by inducing apoptosis and inhibiting mitochondrial respiration. Journal of hazardous materials. 2024 Dec 05;480:136364.

[8]. Blyler G, et al. Selective myelotoxicity of propanil. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1994 May;22(4):505-10.

[9]. Otuechere CA, et al. Pterocarpus mildbraedii (Harms) extract resolves propanil-induced hepatic injury via repression of inflammatory stress responses in Wistar rats. Journal of food biochemistry. 2020 Dec;44(12):e13506.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Propanil-d₅

Ver todos los productos específicos de isoformas Interleukin Related

Ver todos los productos específicos de isoformas Calcium Channel