VU0404251
VU0404251 is a highly potent positive allosteric modulator of mGlu for the study of psychosis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1276013-77-4
- Fòrmula: C19H23FN2O2
- Peso molecular:330.40
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
7.2 nM
Compound: 8v, VU0404251
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Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization
Positive allosteric modulation of rat mGluR5 expressed in human HEK293 cells assessed as calcium mobilization
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[PMID: 22981332] |
| HEK293 | EC50 |
70 nM
Compound: 8v, VU0404251
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Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization
Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization
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[PMID: 22981332] |
Chemical Information
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No. CAS 1276013-77-4
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Peso molecular 330.40
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Fòrmula C19H23FN2O2
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SMILES
O=C(N[C@H](C)C(C)(C)C)C1=CC=C(N=C1)OCC2=CC=CC(F)=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VU0404251 Related Classifications
HY-116067 Related Classifications
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