NUTF2 - nuclear transport factor 2 Gene

Also Known as NTF2; PP15; NTF-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10204

About NUTF2

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,846,933-67,872,567 (from NCBI)

This gene has 14 transcripts (splice variants), 235 orthologues and 2 paralogues. Ubiquitous expression in placenta (RPKM 14.8), testis (RPKM 14.7) and 25 other tissues.

Summary

This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]

NUTF2 Products (5)

mRNA Protein Name
NM_001322038.2 NP_001308967.1 nuclear transport factor 2
NM_001322039.2 NP_001308968.1 nuclear transport factor 2
NM_001322040.2 NP_001308969.1 nuclear transport factor 2
NM_001322041.2 NP_001308970.1 nuclear transport factor 2
NM_005796.3 NP_005787.1 nuclear transport factor 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
19098896 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
7744965 GOA
enables small GTPase binding IDA
IDA: Inferred from direct assay
10679025 GOA
enables small GTPase binding IPI
IPI: Inferred from physical interaction
18266911 GOA
enables structural constituent of nuclear pore IDA
IDA: Inferred from direct assay
7744965 GOA
Biological Process GO Annotation Evidence References Source
involved in protein export from nucleus IDA
IDA: Inferred from direct assay
16449645 GOA
involved in protein import into nucleus IDA
IDA: Inferred from direct assay
7744965 GOA
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
7744965 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
10679025 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NUTF2 Protein Structure

NTF2

NTF2: Nuclear transport factor 2 (NTF2) domain (11 - 121)

  • 0
  • 100
  • 127 a.a.
Protein Preferred Names Protein Names

nuclear transport factor 2

  • placental protein 15

NUTF2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NUTF2 P61970 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 BEND7 Homo sapiens Q8N7W2-2
Y2H Array
32296183
Intra
NUTF2 P61970 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
32296183
Intra
NUTF2 P61970 PAX4 Homo sapiens Q3KNR5
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 PAX4 Homo sapiens Q3KNR5
Validated Y2H
32296183
Intra
NUTF2 P61970 PAX4 Homo sapiens Q3KNR5
Y2H Array
32296183
Intra
NUTF2 P61970 PBX4 Homo sapiens Q9BYU1
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 PBX4 Homo sapiens Q9BYU1
Validated Y2H
32296183
Intra
NUTF2 P61970 PBX4 Homo sapiens Q9BYU1
Y2H Array
32296183
Intra
NUTF2 P61970 NRIP3 Homo sapiens Q9NQ35
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 NRIP3 Homo sapiens Q9NQ35
Validated Y2H
32296183
Intra
NUTF2 P61970 NRIP3 Homo sapiens Q9NQ35
Y2H Array
32296183
Intra
NUTF2 P61970 CKMT1A Homo sapiens P12532
Y2H Array
32296183
Intra
NUTF2 P61970 CKMT1A Homo sapiens P12532
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CLPP Homo sapiens Q16740
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CLPP Homo sapiens Q16740
Validated Y2H
32296183
Intra
NUTF2 P61970 CLPP Homo sapiens Q16740
Y2H Array
32296183
Intra
NUTF2 P61970 BRWD1 Homo sapiens Q9NSI6-4
Validated Y2H
32296183
Intra
NUTF2 P61970 BRWD1 Homo sapiens Q9NSI6-4
Y2H Array
32296183
Intra
NUTF2 P61970 BRWD1 Homo sapiens Q9NSI6-4
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
Intra
NUTF2 P61970 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
NUTF2 P61970 LCE5A Homo sapiens Q5TCM9
Validated Y2H
32296183
Intra
NUTF2 P61970 LCE5A Homo sapiens Q5TCM9
Y2H Array
32296183
Intra
NUTF2 P61970 LCE5A Homo sapiens Q5TCM9
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Array
32296183
Intra
NUTF2 P61970 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 KRTAP9-8 Homo sapiens Q9BYQ0
Validated Y2H
32296183
Intra
NUTF2 P61970 SPATC1L Homo sapiens Q9H0A9-2
Validated Y2H
32296183
Intra
NUTF2 P61970 SPATC1L Homo sapiens Q9H0A9-2
Y2H Array
32296183
Intra
NUTF2 P61970 SPATC1L Homo sapiens Q9H0A9-2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CAMK2G Homo sapiens Q13555-5
Y2H Array
32296183
Intra
NUTF2 P61970 CAMK2G Homo sapiens Q13555-5
Validated Y2H
32296183
Intra
NUTF2 P61970 CAMK2G Homo sapiens Q13555-5
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 YAF2 Homo sapiens Q8IY57-5
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 YAF2 Homo sapiens Q8IY57-5
Y2H Array
32296183
Intra
NUTF2 P61970 YAF2 Homo sapiens Q8IY57-5
Validated Y2H
32296183
Intra
NUTF2 P61970 CHMP4A Homo sapiens Q9BY43-2
Validated Y2H
32296183
Intra
NUTF2 P61970 CHMP4A Homo sapiens Q9BY43-2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CHMP4A Homo sapiens Q9BY43-2
Y2H Array
32296183
Intra
NUTF2 P61970 LCE1C Homo sapiens Q5T751
Validated Y2H
32296183
Intra
NUTF2 P61970 LCE1C Homo sapiens Q5T751
Y2H Array
32296183
Intra
NUTF2 P61970 LCE1C Homo sapiens Q5T751
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CCDC150 Homo sapiens Q8NCX0-3
Validated Y2H
32296183
Intra
NUTF2 P61970 CCDC150 Homo sapiens Q8NCX0-3
Y2H Array
32296183
Intra
NUTF2 P61970 CCDC150 Homo sapiens Q8NCX0-3
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 TEX35 Homo sapiens Q5T0J7-2
Validated Y2H
32296183
Intra
NUTF2 P61970 TEX35 Homo sapiens Q5T0J7-2
Y2H Array
32296183
Intra
NUTF2 P61970 TEX35 Homo sapiens Q5T0J7-2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 THAP3 Homo sapiens Q8WTV1
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 THAP3 Homo sapiens Q8WTV1
Y2H Array
32296183
Intra
NUTF2 P61970 THAP3 Homo sapiens Q8WTV1
Validated Y2H
32296183
Intra
NUTF2 P61970 UBAP2 Homo sapiens Q5T6F2
Validated Y2H
32296183
Intra
NUTF2 P61970 UBAP2 Homo sapiens Q5T6F2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 UBAP2 Homo sapiens Q5T6F2
Y2H Array
32296183
Intra
NUTF2 P61970 ZMAT2 Homo sapiens Q96NC0
Y2H Array
32296183
Intra
NUTF2 P61970 ZMAT2 Homo sapiens Q96NC0
Validated Y2H
32296183
Intra
NUTF2 P61970 ZMAT2 Homo sapiens Q96NC0
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 MRNIP Homo sapiens Q6NTE8
Validated Y2H
32296183
Intra
NUTF2 P61970 MRNIP Homo sapiens Q6NTE8
Y2H Array
32296183
Intra
NUTF2 P61970 MRNIP Homo sapiens Q6NTE8
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 PHF11 Homo sapiens Q9UIL8
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 PHF11 Homo sapiens Q9UIL8
Validated Y2H
32296183
Intra
NUTF2 P61970 PHF11 Homo sapiens Q9UIL8
Y2H Array
32296183
Intra
NUTF2 P61970 RAN Homo sapiens P62826
Comig Non-Denat Gel
19098896
Intra
NUTF2 P61970 RAN Homo sapiens P62826
Anti Tag CoIP
35271311
Intra
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Array
31515488
Intra
NUTF2 P61970 NUP62 Homo sapiens P37198
Validated Y2H
25416956
Intra
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Array
32296183
Intra
NUTF2 P61970 NUP62 Homo sapiens P37198
Y2H Array
25416956
Intra
NUTF2 P61970 SPRY4 Homo sapiens Q9C004
Validated Y2H
32296183
Intra
NUTF2 P61970 SPRY4 Homo sapiens Q9C004
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 SPRY4 Homo sapiens Q9C004
Y2H Array
32296183
Intra
NUTF2 P61970 PCNA Homo sapiens P12004
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 PCNA Homo sapiens P12004
Y2H Array
32296183
Intra
NUTF2 P61970 PFKP Homo sapiens Q01813
Validated Y2H
32296183
Intra
NUTF2 P61970 PFKP Homo sapiens Q01813
Y2H Array
32296183
Intra
NUTF2 P61970 PFKP Homo sapiens Q01813
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 MYOZ3 Homo sapiens Q8TDC0
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 MYOZ3 Homo sapiens Q8TDC0
Validated Y2H
32296183
Intra
NUTF2 P61970 MYOZ3 Homo sapiens Q8TDC0
Y2H Array
32296183
Intra
NUTF2 P61970 NUTF2 Homo sapiens P61970
Comig Non-Denat Gel
19098896
Intra
NUTF2 P61970 NUTF2 Homo sapiens P61970
Y2H Array
25416956
Intra
NUTF2 P61970 NUTF2 Homo sapiens P61970
GMS
19098896
Intra
NUTF2 P61970 PPP1R16A Homo sapiens Q96I34
Validated Y2H
32296183
Intra
NUTF2 P61970 PPP1R16A Homo sapiens Q96I34
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 PPP1R16A Homo sapiens Q96I34
Y2H Array
32296183
Intra
NUTF2 P61970 CCDC106 Homo sapiens Q9BWC9
Y2H Array
32296183
Intra
NUTF2 P61970 CCDC106 Homo sapiens Q9BWC9
Validated Y2H
32296183
Intra
NUTF2 P61970 CCDC106 Homo sapiens Q9BWC9
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 HMG20B Homo sapiens Q9P0W2
Y2H Array
32296183
Intra
NUTF2 P61970 HMG20B Homo sapiens Q9P0W2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 HMG20B Homo sapiens Q9P0W2
Validated Y2H
32296183
Intra
NUTF2 P61970 LENG1 Homo sapiens Q96BZ8
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 LENG1 Homo sapiens Q96BZ8
Validated Y2H
32296183
Intra
NUTF2 P61970 LENG1 Homo sapiens Q96BZ8
Y2H Array
32296183
Intra
NUTF2 P61970 HMG20A Homo sapiens Q9NP66
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 HMG20A Homo sapiens Q9NP66
Validated Y2H
32296183
Intra
NUTF2 P61970 HMG20A Homo sapiens Q9NP66
Y2H Array
32296183
Intra
NUTF2 P61970 NUP54 Homo sapiens Q7Z3B4
Validated Y2H
32296183
Intra
NUTF2 P61970 NUP54 Homo sapiens Q7Z3B4
Y2H Array
32296183
Intra
NUTF2 P61970 NUP54 Homo sapiens Q7Z3B4
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 NME1 Homo sapiens P15531
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 NME1 Homo sapiens P15531
Y2H Array
32296183
Intra
NUTF2 P61970 FAM50B Homo sapiens Q9Y247
Validated Y2H
32296183
Intra
NUTF2 P61970 FAM50B Homo sapiens Q9Y247
Y2H Array
32296183
Intra
NUTF2 P61970 FAM50B Homo sapiens Q9Y247
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CHCHD3 Homo sapiens Q9NX63
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 CHCHD3 Homo sapiens Q9NX63
Validated Y2H
32296183
Intra
NUTF2 P61970 CHCHD3 Homo sapiens Q9NX63
Y2H Array
32296183
Intra
NUTF2 P61970 NME4 Homo sapiens O00746
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 NME4 Homo sapiens O00746
Y2H Array
32296183
Intra
NUTF2 P61970 RPRD1B Homo sapiens Q9NQG5
Validated Y2H
32296183
Intra
NUTF2 P61970 RPRD1B Homo sapiens Q9NQG5
Y2H Array
32296183
Intra
NUTF2 P61970 RPRD1B Homo sapiens Q9NQG5
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra
NUTF2 P61970 LASP1 Homo sapiens Q14847-2
Validated Y2H
32296183
Intra
NUTF2 P61970 KHDC4 Homo sapiens Q7Z7F0-4
Validated Y2H
32296183
Intra
NUTF2 P61970 KHDC4 Homo sapiens Q7Z7F0-4
Y2H Array
32296183
Intra
NUTF2 P61970 KHDC4 Homo sapiens Q7Z7F0-4
Y2H Prey Pooling
32296183
Intra
NUTF2 P61970 KRT86 Homo sapiens O43790
Y2H Array
32296183
Intra
NUTF2 P61970 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

NUTF2 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810253 NTF2 Antibody (YA9597) WB, IP, ELISA human, mouse, rat
HY-P811120 PP15 Antibody WB, IHC-P, ICC/IF Human, Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09705 NUTF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NUTF2 VGNC VGNC:97543
Rattus norvegicus NUTF2 RGD RGD:1359213
Mus musculus NUTF2 MGD MGI:1915301
Bos taurus NUTF2 VGNC VGNC:32371
Others NUTF2 NCBI