CDKN2A - cyclin dependent kinase inhibitor 2A Gene
Also Known as ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A
Species: Homo sapiens
About CDKN2A
This gene has 14 transcripts (splice variants), 87 orthologues, 1 paralogue and is associated with 234 phenotypes. Low expression observed in reference dataset.
Summary
This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the Other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein Ligase MDM2, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK Inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene. [provided by RefSeq, Sep 2012]
CDKN2A Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_000077.5 | NP_000068.1 | cyclin-dependent kinase inhibitor 2A isoform p16INK4a |
| NM_001195132.2 | NP_001182061.1 | cyclin-dependent kinase inhibitor 2A isoform p16gamma |
| NM_001363763.2 | NP_001350692.1 | cyclin-dependent kinase inhibitor 2A isoform 6 |
| NM_058195.4 | NP_478102.2 | cyclin-dependent kinase inhibitor 2A isoform p14ARF |
| NM_058197.5 | NP_478104.2 | cyclin-dependent kinase inhibitor 2A isoform p12 |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
16243918 | GOA |
| located in mitochondrion |
IMP
IMP: Inferred from mutant phenotype
|
25217637 | GOA |
| colocalizes with nuclear body |
IDA
IDA: Inferred from direct assay
|
10360174 | GOA |
| located in nucleolus |
IDA
IDA: Inferred from direct assay
|
10360174 | GOA |
| located in nucleoplasm |
IDA
IDA: Inferred from direct assay
|
10360174 | GOA |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
11800646 | GOA |
| part of protein-containing complex |
IDA
IDA: Inferred from direct assay
|
9529249 | GOA |
| located in senescence-associated heterochromatin focus |
IDA
IDA: Inferred from direct assay
|
16901784 | GOA |
CDKN2A Protein Structure
Ank: Ankyrin repeat (18 - 42)
Ank_2: Ankyrin repeats (3 copies) (52 - 133)
- 0
- 100
- 156 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cyclin-dependent kinase inhibitor 2A |
|
CDKN2A Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
CDKN2A | P42771 | CDK4 | Homo sapiens | P11802 | 17955473 | |
|
Intra
|
CDKN2A | P42771 | CDK4 | Homo sapiens | P11802 | 24855949 | |
|
Intra
|
CDKN2A | P42771 | CDK4 | Homo sapiens | P11802 | 17909018 | |
|
Intra
|
CDKN2A | P42771 | CDK4 | Homo sapiens | P11802 | 17517622 | |
|
Intra
|
CDKN2A | P42771 | CDK4 | Homo sapiens | P11802 | 24855949 | |
|
Intra
|
CDKN2A | P42771 | CDK4 | Homo sapiens | P11802 | 35271311 | |
|
Intra
|
CDKN2A | P42771 | CDK6 | Homo sapiens | Q00534 | 17909018 | |
|
Intra
|
CDKN2A | P42771 | CDK6 | Homo sapiens | Q00534 | 35271311 | |
|
Intra
|
CDKN2A | P42771 | CDK6 | Homo sapiens | Q00534 | 17955473 | |
|
Intra
|
CDKN2A | P42771 | CDK6 | Homo sapiens | Q00534 | 9751050 | |
|
Intra
|
CDKN2A | P42771 | CDK6 | Homo sapiens | Q00534 | 24855949 | |
|
Intra
|
CDKN2A | P42771 | HNRNPU | Homo sapiens | Q00839 | 21988832 | |
|
Intra
|
CDKN2A | P42771 | HNRNPU | Homo sapiens | Q00839 | 21988832 | |
|
Intra
|
CDKN2A | P42771 | PCNA | Homo sapiens | P12004 | 17955473 | |
|
Intra
|
CDKN2A | P42771 | PCNA | Homo sapiens | P12004 | 17955473 | |
|
Intra
|
CDKN2A | P42771 | GMNN | Homo sapiens | O75496 | 15232106 | |
|
Intra
|
CDKN2A | P42771 | GMNN | Homo sapiens | O75496 | 27229929 | |
|
Intra
|
CDKN2A | P42771 | MCM6 | Homo sapiens | Q14566 | 17955473 | |
|
Intra
|
CDKN2A | P42771 | MCM6 | Homo sapiens | Q14566 | 17955473 | |
|
Intra
|
CDKN2A | P42771 | CRELD2 | Homo sapiens | Q6UXH1 | 21988832 | |
|
Intra
|
CDKN2A | P42771 | CRELD2 | Homo sapiens | Q6UXH1 | 21988832 | |
|
Intra
|
CDKN2A | P42771 | TDRD7 | Homo sapiens | Q8NHU6 | 21988832 | |
|
Intra
|
CDKN2A | Q8N726 | EGR1 | Homo sapiens | P18146 | 19057511 | |
|
Intra
|
CDKN2A | Q8N726 | SP1 | Homo sapiens | P08047 | 21555589 | |
|
Intra
|
CDKN2A | Q8N726 | C1QBP | Homo sapiens | Q07021 | 17486078 | |
|
Intra
|
CDKN2A | Q8N726 | C1QBP | Homo sapiens | Q07021 | 17486078 | |
|
Intra
|
CDKN2A | Q8N726 | MDM2 | Homo sapiens | Q00987 | 20713054 | |
|
Intra
|
CDKN2A | Q8N726 | ZNF420 | Homo sapiens | Q8TAQ5 | 20713054 | |
|
Intra
|
CDKN2A | Q8N726 | ZNF420 | Homo sapiens | Q8TAQ5 | 20713054 | |
|
Intra
|
CDKN2A | Q8N726 | HUWE1 | Homo sapiens | Q7Z6Z7 | 15989956 | |
|
Intra
|
CDKN2A | Q8N726 | HUWE1 | Homo sapiens | Q7Z6Z7 | 15989956 | |
|
Intra
|
CDKN2A | Q8N726 | HUWE1 | Homo sapiens | Q7Z6Z7 | 15989956 | |
|
Intra
|
CDKN2A | Q8N726 | MTA1 | Homo sapiens | Q13330 | 21555589 | |
|
Intra
|
CDKN2A | Q8N726 | DAXX | Homo sapiens | Q9UER7 | 18583933 | |
|
Intra
|
CDKN2A | Q8N726 | DAXX | Homo sapiens | Q9UER7 | 18583933 | |
|
Intra
|
CDKN2A | Q8N726 | DAXX | Homo sapiens | Q9UER7 | 18583933 | |
|
Intra
|
CDKN2A | Q8N726 | NPM1 | Homo sapiens | P06748 | 15989956 | |
|
Intra
|
CDKN2A | Q8N726 | MYCN | Homo sapiens | P04198 | 17289033 | |
|
Intra
|
CDKN2A | Q8N726 | MYCN | Homo sapiens | P04198 | 17289033 | |
|
Cross
|
CDKN2A | Q8N726 | EBNA-LP | Epstein-Barr virus | Q8AZK7 | 12740913 | |
|
Cross
|
CDKN2A | Q8N726 | EBNA-LP | Epstein-Barr virus | Q8AZK7 | 12740913 | |
|
Cross
|
CDKN2A | Q8N726 | EBNA-LP | Epstein-Barr virus | Q8AZK7 | 12740913 |
Recombinant CDKN2A Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P72785 | CDKN2A Protein, Human | P42771 (E2-D156) | ≥ 95%, as determined by reducing SDS-PAGE. |
CDKN2A Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P80615 | CDKN2A/p16INK4a Antibody (YA508) | WB, IP | Human, Mouse |
| HY-P80615A | CDKN2A/p16INK4a Antibody (YA508)(PBS only) | WB, IP | Human, Mouse |
| HY-P80992 | CDKN2A/p16INK4a Antibody (YA3494) | WB, IHC-P | Human |
| HY-P84321 | CDKN2A/p16INK4a Antibody (YA4018) | WB, IHC-P, FC, ELISA | Human |
| HY-P84321A | CDKN2A/p16INK4a Antibody (YA4018)(PBS only) | WB, IHC-P, FC, ELISA | Human |
| HY-P85830 | CDKN2A/p16INK4a Antibody (YA5522) | IHC-P, WB, ICC/IF, ELISA | Human |
| HY-P86438 | CDKN2A/p16INK4a Antibody (YA6130) | WB, ICC/IF, IP, ELISA | Human, Mouse, Rat |
| HY-P86609 | CDKN2A/p14ARF Antibody (YA6301) | WB, ICC/IF, IP, ELISA | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Melanoma, Cutaneous Malignant 2 |
|
|
| Melanoma-Pancreatic Cancer Syndrome |
|
|
| Melanoma-Astrocytoma Syndrome |
|
|
| Hereditary Melanoma |
|
|
| Dysplastic Nevus Syndrome |
|
|
| Melanoma |
|
|
| Melanoma, Cutaneous Malignant 1 |
|
|
| Lip And Oral Cavity Cancer |
|
|
| B-Lymphoblastic Leukemia/Lymphoma With Recurrent Genetic Abnormality |
|
|
| Precursor T-Cell Acute Lymphoblastic Leukemia |
|
|
| Bap1 Tumor Predisposition Syndrome |
|
|
| Inherited Cancer-Predisposing Syndrome |
|
|
| Ovarian Cancer |
|
|
| Lipoprotein Quantitative Trait Locus |
|
|
| Pancreatic Adenocarcinoma |
|
|
| Li-Fraumeni Syndrome |
|
|
| Cervical Adenocarcinoma |
|
|
| Skin Melanoma |
|
|
| Cervical Intraepithelial Neoplasia |
|
|
| Papilloma |
|
|
| Adenocarcinoma |
|
|
| Human Papillomavirus Infectious Disease |
|
|
| Tonsil Cancer |
|
|
| Penile Cancer |
|
|
| Skin Squamous Cell Carcinoma |
|
|
| Bile Duct Cancer |
|
|
| Oligodendroglioma |
|
|
| Tonsil Squamous Cell Carcinoma |
|
|
| Gallbladder Adenoma |
|
|
| Bladder Urothelial Carcinoma |
|
|
| Malignant Peripheral Nerve Sheath Tumor |
|
|
| Adenocarcinoma In Situ |
|
|
| Gastric Adenocarcinoma |
|
|
| Suppression Of Tumorigenicity 12 |
|
|
| Retinoblastoma |
|
|
| Barrett Esophagus |
|
|
| Pancreatic Cancer |
|
|
| Renal Cell Carcinoma, Papillary, 1 |
|
|
| Lung Squamous Cell Carcinoma |
|
|
| Head And Neck Cancer |
|
|
| Vulva Cancer |
|
|
| Lung Cancer |
|
|
| Anaplastic Astrocytoma |
|
|
| Squamous Cell Carcinoma |
|
|
| Esophageal Cancer |
|
|
| Cervical Squamous Cell Carcinoma |
|
|
| Endocervical Carcinoma |
|
|
| Endometrial Cancer |
|
|
| Anal Squamous Cell Carcinoma |
|
|
| Keratinizing Squamous Cell Carcinoma |
|
|
| Malignant Pleural Mesothelioma |
|
|
| Oropharynx Cancer |
|
|
| Persistent Hyperplastic Primary Vitreous |
|
|
| Inverted Papilloma |
|
|
| Bladder Cancer |
|
|
| Squamous Cell Carcinoma, Head And Neck |
|
|
| Melanoma In Congenital Melanocytic Nevus |
|
|
| Anaplastic Oligodendroglioma |
|
|
| Laryngeal Squamous Cell Carcinoma |
|
|
| Adenomyoma |
|
|
| Anus Cancer |
|
|
| Neurofibroma |
|
|
| Tonsillar Fossa Cancer |
|
|
| Scrotum Basal Cell Carcinoma |
|
|
| Lung Cancer Susceptibility 3 |
|
|
| Soft Palate Cancer |
|
|
| Fallopian Tube Squamous Cell Carcinoma |
|
|
| Penile Urethral Cancer |
|
|
| Plasma Cell Leukemia |
|
|
| Lung Benign Neoplasm |
|
|
| Vulvar Disease |
|
|
| Ulceration Of Vulva |
|
|
| Anus Disease |
|
|
| Glioblastoma |
|
|
| Penile Benign Neoplasm |
|
|
| Verrucous Carcinoma |
|
|
| Penile Disease |
|
|
| Pilocytic Astrocytoma |
|
|
| Tonsillar Pillar Cancer |
|
|
| Urinary Bladder Inverted Papilloma |
|
|
| Ocular Melanoma |
|
|
| Pancreatic Ductal Carcinoma |
|
|
| B-Lymphoblastic Leukemia/Lymphoma |
|
|
| Mantle Cell Lymphoma |
|
|
| Cholecystitis |
|
|
| Adenoma |
|
|
| Childhood Acute Lymphocytic Leukemia |
|
|
| Endometrial Squamous Cell Carcinoma |
|
|
| Hepatocellular Carcinoma |
|
|
| Endometrial Mucinous Adenocarcinoma |
|
|
| Liposarcoma |
|
|
| Vulva Squamous Cell Carcinoma |
|
|
| Vaginal Cancer |
|
|
| Colorectal Cancer |
|
|
| Bilateral Breast Cancer |
|
|
| Gallbladder Cancer |
|
|
| Nasal Cavity Cancer |
|
|
| Benign Mesothelioma |
|
|
| Lynch Syndrome |
|
|
| Nasopharyngeal Carcinoma |
|
|
| Suppressor Of Tumorigenicity 3 |
|
|
| Mesothelioma, Malignant |
|
|
| Atypical Neurofibroma |
|
|
| Carcinosarcoma |
|
|
| Esophagus Verrucous Carcinoma |
|
|
| Leiomyosarcoma |
|
|
| Rectal Disease |
|
|
| Early Invasive Cervical Adenocarcinoma |
|
|
| Basaloid Squamous Cell Carcinoma |
|
|
| Hypopharynx Cancer |
|
|
| Uterus Carcinoma In Situ |
|
|
| Melanoma, Uveal |
|
|
| Cervical Cancer |
|
|
| Leukemia |
|
|
| Laryngeal Benign Neoplasm |
|
|
| Borst-Jadassohn Intraepidermal Carcinoma |
|
|
| Plasmacytoma |
|
|
| Keratosis |
|
|
| Bone Cancer |
|
|
| Chordoma |
|
|
| Cervix Endometriosis |
|
|
| B-Cell Lymphoma |
|
|
| Cervix Uteri Carcinoma In Situ |
|
|
| Cervical Basaloid Squamous Cell Carcinoma |
|
|
| Anal Margin Squamous Cell Carcinoma |
|
|
| Gastric Cancer |
|
|
| Endometrial Transitional Cell Carcinoma |
|
|
| Vulvar Seborrheic Keratosis |
|
|
| Endometrial Hyperplasia |
|
|
| Chronic Cervicitis |
|
|
| Mediastinum Liposarcoma |
|
|
| Spitzoid Melanoma |
|
|
| Skin Carcinoma |
|
|
| Nodular Malignant Melanoma |
|
|
| Bizarre Leiomyoma |
|
|
| Trachea Carcinoma In Situ |
|
|
| Male Reproductive Organ Benign Neoplasm |
|
|
| Cervical Adenoid Cystic Carcinoma |
|
|
| Neurofibromatosis |
|
|
| Teratoma |
|
|
| Respiratory System Benign Neoplasm |
|
|
| Salivary Gland Carcinoma |
|
|
| Squamous Cell Papilloma |
|
|
| Burkitt Lymphoma |
|
|
| Ampulla Of Vater Cancer |
|
|
| Basal Cell Carcinoma |
|
|
| Adenoid Cystic Carcinoma |
|
|
| Lymphoma |
|
|
| Retinal Cancer |
|
|
| Peritoneal Mesothelioma |
|
|
| Inverted Transitional Papilloma |
|
|
| Ewing Sarcoma |
|
|
| Supraglottis Neoplasm |
|
|
| Cervical Mucinous Adenocarcinoma |
|
|
| Phimosis |
|
|
| Pleomorphic Xanthoastrocytoma |
|
|
| Cholangitis |
|
|
| Paraganglioma |
|
|
| Leukemia, Acute Lymphoblastic |
|
|
| Thymoma |
|
|
| Sebaceous Adenocarcinoma |
|
|
| Tongue Carcinoma |
|
|
| Small Intestine Cancer |
|
|
| Keratosis, Seborrheic |
|
|
| Idh-Wildtype Glioblastoma |
|
|
| High Grade Glioma |
|
|
| Pre-Malignant Neoplasm |
|
|
| Scrotal Carcinoma |
|
|
| Endocervical Adenocarcinoma |
|
|
| Acral Lentiginous Melanoma |
|
|
| Follicular Lymphoma |
|
|
| Vulval Paget'S Disease |
|
|
| Lip Cancer |
|
|
| Conjunctival Squamous Cell Carcinoma |
|
|
| Larynx Squamous Papilloma |
|
|
| Kidney Cancer |
|
|
| Middle Ear Squamous Cell Carcinoma |
|
|
| B-Lymphoblastic Leukemia/Lymphoma, Bcr-Abl1-Like |
|
|
| Anogenital Venereal Wart |
|
|
| Sarcomatoid Mesothelioma |
|
|
| Peritoneum Cancer |
|
|
| Diffuse Astrocytoma |
|
|
| Acanthoma |
|
|
| Mucosal Melanoma |
|
|
| Small Cell Cancer Of The Lung |
|
|
| Familial Retinoblastoma |
|
|
| Plexiform Neurofibroma |
|
|
| Lymphoepithelioma-Like Carcinoma |
|
|
| Fallopian Tube Endometrioid Adenocarcinoma |
|
|
| Sinonasal Undifferentiated Carcinoma |
|
|
| Anus Benign Neoplasm |
|
|
| Actinic Keratosis |
|
|
| Ocular Cancer |
|
|
| Hemangioma |
|
|
| Paranasal Sinus Cancer |
|
|
| Vagina Leiomyoma |
|
|
| Cervical Clear Cell Adenocarcinoma |
|
|
| Cervix Carcinoma |
|
|
| Cervicitis |
|
|
| Rhabdomyosarcoma |
|
|
| Anal Margin Carcinoma |
|
|
| In Situ Carcinoma |
|
|
| Papillary Squamous Carcinoma |
|
|
| Female Breast Cancer |
|
|
| Cervical Adenosquamous Carcinoma |
|
|
| Osteogenic Sarcoma |
|
|
| Vulva Basal Cell Carcinoma |
|
|
| Male Urethral Cancer |
|
|
| Adult Malignant Schwannoma |
|
|
| Conjunctival Cancer |
|
|
| Meningioma, Familial |
|
|
| Bone Squamous Cell Carcinoma |
|
|
| Lung Adenoma |
|
|
| Well-Differentiated Liposarcoma |
|
|
| Hepatoblastoma |
|
|
| Serous Cystadenocarcinoma |
|
|
| Central Nervous System Benign Neoplasm |
|
|
| Myelodysplastic Syndrome |
|
|
| Angelman Syndrome |
|
|
| Papillary Adenofibroma |
|
|
| Anal Canal Paget'S Disease |
|
|
| Diffuse Glioma, H3 G34 Mutant |
|
|
| Skin Sarcoma |
|
|
| Anus Basaloid Carcinoma |
|
|
| Pheochromocytoma |
|
|
| Medulloblastoma |
|
|
| Malignant Spindle Cell Melanoma |
|
|
| Low Grade Glioma |
|
|
| Pancreatoblastoma |
|
|
| Pleural Cancer |
|
|
| Neurofibrosarcoma |
|
|
| Atrophic Vulva |
|
|
| Myelofibrosis |
|
|
| Esophagus Adenocarcinoma |
|
|
| Vaginal Benign Neoplasm |
|
|
| Female Urethral Cancer |
|
|
| Fragile X Syndrome |
|
|
| Inflammatory Liposarcoma |
|
|
| Penis Basal Cell Carcinoma |
|
|
| Large Congenital Melanocytic Nevus |
|
|
| Spinal Cord Disease |
|
|
| Mucinous Adenocarcinoma |
|
|
| Neurilemmomatosis |
|
|
| Mixed Glioma |
|
|
| Endometrial Adenocarcinoma |
|
|
| Retinal Disease |
|
|
| Supratentorial Cancer |
|
|
| Vulvar Eccrine Porocarcinoma |
|
|
| Wolf-Hirschhorn Syndrome |
|
|
| Breast Cancer |
|
|
| Cerebral Ventricle Cancer |
|
|
| Mixed Cell Type Cancer |
|
|
| Neuroblastoma |
|
|
| Lymphohistiocytoid Mesothelioma |
|
|
| Osteogenesis Imperfecta, Type Xiii |
|
|
| Ovarian Cystadenocarcinoma |
|
|
| Brain Glioma |
|
|
| Barrett'S Adenocarcinoma |
|
|
| Dedifferentiated Liposarcoma |
|
|
| Ovarian Seromucinous Carcinoma |
|
|
| Muir-Torre Syndrome |
|
|
| Gastric Liposarcoma |
|
|
| Bladder Clear Cell Adenocarcinoma |
|
|
| Reproductive Organ Benign Neoplasm |
|
|
| Ovary Adenocarcinoma |
|
|
| Breast Carcinoma In Situ |
|
|
| Ductal Carcinoma In Situ |
|
|
| Sensory System Disease |
|
|
| Muscle Cancer |
|
|
| Pleural Disease |
|
|
| Type 2 Diabetes Mellitus |
|
|
| Ovarian Serous Cystadenocarcinoma |
|
|
| Prostate Cancer |
|
|
| Uterine Benign Neoplasm |
|
|
| Cell Type Benign Neoplasm |
|
|
| Myocardial Infarction |
|
|
| Malignant Exocrine Pancreas Neoplasm |
|
|
| Laryngeal Small Cell Carcinoma |
|
|
| Gallbladder Small Cell Carcinoma |
|
|
| Diabetes Mellitus |
|
|
| Mature B-Cell Neoplasm |
|
|
| Uterine Corpus Cancer |
|
|
| Pilomyxoid Astrocytoma |
|
|
| Giant Cell Glioblastoma |
|
|
| Infratentorial Cancer |
|
|
| Tetralogy Of Fallot |
|
|
| Neurofibromatosis, Type I |
|
|
| Intestinal Benign Neoplasm |
|
|
| Tongue Disease |
|
|
| Myxofibrosarcoma |
|
|
| Hereditary Breast Ovarian Cancer Syndrome |
|
|
| Atypical Teratoid Rhabdoid Tumor |
|
|
| Cholangiocarcinoma |
|
|
| Infiltrating Angiolipoma |
|
|
| Gliosarcoma |
|
|
| Gastrointestinal Stromal Tumor |
|
|
| Epidermodysplasia Verruciformis 1 |
|
|
| Intravascular Fasciitis |
|
|
| Eye Disease |
|
|
| Renal Cell Carcinoma, Nonpapillary |
|
|
| Retinitis Pigmentosa 11 |
|
|
| Colonic Benign Neoplasm |
|
|
| Cowden Syndrome |
|
|
| Bone Osteosarcoma |
|
|
| Breast Adenocarcinoma |
|
|
| Skin Disease |
|
|
| Peripheral Nervous System Disease |
|
|
| Leukemia, Acute Myeloid |
|
|
| Dyskeratosis Congenita |
|
|
| Wilms Tumor 1 |
|
|
| Nervous System Disease |
|
|
| Rasopathy |
|
|
| Connective Tissue Disease |
|
|
| Leukemia, Chronic Lymphocytic |
|
|
| Fanconi Anemia, Complementation Group A |
|
|
| Retinitis Pigmentosa |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | CDKN2A | RGD | RGD:2323 |
| Mus musculus | CDKN2A | MGD | MGI:104738 |