CEBPG - CCAAT enhancer binding protein gamma Gene

Also Known as GPE1BP; IG/EBP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1054

About CEBPG

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:33,373,709-33,382,686 (from NCBI)

This gene has 3 transcripts (splice variants), 129 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 20.4), colon (RPKM 19.6) and 25 other tissues.

Summary

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each Other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]

CEBPG Products (2)

mRNA Protein Name
NM_001252296.2 NP_001239225.1 CCAAT/enhancer-binding protein gamma
NM_001806.4 NP_001797.1 CCAAT/enhancer-binding protein gamma

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7665092 GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
15833715 GOA
enables DNA-binding transcription factor binding IDA
IDA: Inferred from direct assay
7665092 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
7665092 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
7665092 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA repair IEP
IEP: Inferred from expression pattern
16255782 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15833715 GOA
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16255782 GOA
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase II transcription regulator complex IPI
IPI: Inferred from physical interaction
20102225 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CEBPG Protein Structure

bZIP_2

bZIP_2: Basic region leucine zipper (62 - 114)

  • 0
  • 100
  • 150 a.a.
Protein Preferred Names Protein Names

CCAAT/enhancer-binding protein gamma

  • CCAAT/enhancer binding protein (C/EBP), gamma

CEBPG Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CEBPG P53567 DDIT3 Homo sapiens P35638-2
Validated Y2H
25416956
Intra
CEBPG P53567 DDIT3 Homo sapiens P35638-2
Y2H Array
25416956
Intra
CEBPG P53567 BATF3 Homo sapiens Q9NR55
FRET
23661758
Intra
CEBPG P53567 ATF2 Homo sapiens P15336
FRET
23661758
Intra
CEBPG P53567 ATF2 Homo sapiens P15336
Anti Tag CoIP
33961781
Intra
CEBPG P53567 CEBPA Homo sapiens P49715
Peptide Array
20102225
Intra
CEBPG P53567 PFDN6 Homo sapiens O15212
Y2H Prey Pooling
32296183
Intra
CEBPG P53567 PFDN6 Homo sapiens O15212
Y2H Array
32296183
Intra
CEBPG P53567 ATF4 Homo sapiens P18848
Y2H Prey Pooling
25416956
Intra
CEBPG P53567 ATF4 Homo sapiens P18848
Y2H Prey Pooling
32296183
Intra
CEBPG P53567 ATF4 Homo sapiens P18848
FRET
23661758
Intra
CEBPG P53567 ATF4 Homo sapiens P18848
Y2H Array
25416956
Intra
CEBPG P53567 ATF4 Homo sapiens P18848
Y2H Array
32296183
Intra
CEBPG P53567 ATF4 Homo sapiens P18848
Validated Y2H
25416956
Intra
CEBPG P53567 ATF5 Homo sapiens Q9Y2D1
FRET
23661758
Intra
CEBPG P53567 ATF5 Homo sapiens Q9Y2D1
Y2H Prey Pooling
32296183
Intra
CEBPG P53567 ATF5 Homo sapiens Q9Y2D1
Validated Y2H
32296183
Intra
CEBPG P53567 ATF5 Homo sapiens Q9Y2D1
Y2H Array
32296183
Intra
CEBPG P53567 ATF5 Homo sapiens Q9Y2D1
Y2H Array
20211142
Intra
CEBPG P53567 ATF3 Homo sapiens P18847
Peptide Array
20102225
Intra
CEBPG P53567 ATF3 Homo sapiens P18847
FRET
23661758
Intra
CEBPG P53567 MLLT6 Homo sapiens P55198
Y2H Pooling
16189514
Intra
CEBPG P53567 DDIT3 Homo sapiens P35638
FRET
23661758
Intra
CEBPG P53567 DDIT3 Homo sapiens P35638
Y2H Pooling
16189514
Intra
CEBPG P53567 DDIT3 Homo sapiens P35638
Peptide Array
20102225
Intra
CEBPG P53567 DDIT3 Homo sapiens P35638
Y2H Array
20211142
Intra
CEBPG P53567 BATF2 Homo sapiens Q8N1L9
FRET
23661758
Intra
CEBPG P53567 BATF Homo sapiens Q16520
FRET
23661758
Intra
CEBPG P53567 ATF7 Homo sapiens P17544
Anti Tag CoIP
33961781
Intra
CEBPG P53567 CEBPD Homo sapiens P49716
Peptide Array
20102225
Intra
CEBPG P53567 JUN Homo sapiens P05412
FRET
23661758
Intra
CEBPG P53567 JUN Homo sapiens P05412
Anti Tag CoIP
33961781
Intra
CEBPG P53567 FOS Homo sapiens P01100
SLC
31467278
Intra
CEBPG P53567 CEBPB Homo sapiens P17676
Peptide Array
20102225
Cross
CEBPG P53567 HBZ Human T-cell leukemia virus 1 P0C746
Peptide Array
20102225
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CEBPG Proteins

Cat. No. Product Name Accession Purity
HY-P74254 CEBP gamma/CEBPG Protein, Human (His) P53567 (P39-N147) ≥ 90%, as determined by reducing SDS-PAGE.

CEBPG Antibodies

Cat. No. Product Name Application Reactivity
HY-P811128 C/EBP gamma Antibody WB, IHC-P, ICC/IF Human, Mouse, Rat
HY-P89763 CEBPG Antibody (YA9107) WB, IP, ELISA human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02449 CEBPG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21520 Cebpg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28038 Cebpg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CEBPG MGD MGI:104982
Bos taurus CEBPG VGNC VGNC:27163
Macaca mulatta CEBPG VGNC VGNC:71003
Canis familiaris CEBPG VGNC VGNC:39089
Rattus norvegicus CEBPG RGD RGD:2330
Others CEBPG NCBI