Smarca2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361745

Summary

Enables chromatin binding activity. Involved in spermatid development. Predicted to be located in chromatin; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of SWI/SNF complex; nBAF complex; and npBAF complex. Predicted to be active in nucleus. Orthologous to human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2). [provided by Alliance of Genome Resources, Apr 2022]

Smarca2 Products (1)

mRNA Protein Name
NM_001004446.1 NP_001004446.1 probable global transcription activator SNF2L2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
15574597 RGD
Biological Process GO Annotation Evidence References Source
involved in spermatid development IEP
IEP: Inferred from expression pattern
22215678 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable global transcription activator SNF2L2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-159607 PRT3789 Degrader 98.08% Phase 2

Pre-clinical Phase

Bioactive Molecules (41)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145388 AU-15330 Degrader 99.89% Unkown
HY-128359 ACBI1 Degrader 99.92% Unkown
HY-44012 SMARCA-BD ligand 1 for PROTAC Ligand 99.07% Unkown
HY-44012B SMARCA-BD ligand 1 for PROTAC hydrochloride Ligand 99.24% Unkown
HY-44012A SMARCA-BD ligand 1 for PROTAC dihydrochloride Ligand 98.08% Unkown
HY-46618 SMARCA2/4-ligand-8 Ligand 99.66% Unkown
HY-148381 A947 Degrader / Unkown
HY-170824 SMD-3236 Degrader / Unkown
HY-185075 FHD-909 Inhibitor / Unkown
HY-181909 PROTAC SMARCA2 degrader-36 Degrader / Unkown
HY-181910 SMARCA2 ligand-19 Ligand / Unkown
HY-168237 SMARCA2 ligand-10 Ligand / Unkown
HY-159460 PROTAC SMARCA2/4 degrader-8 Degrader / Unkown
HY-169280 PXR Ligand 2 / Unkown
HY-169487 SMARCA2 ligand-12 / Unkown
HY-180932 SMARCA2 ligand-17 Ligand / Unkown
HY-44824 SMARCA2 ligand-13 Ligand / Unkown
HY-168252 BRM/BRG1 ligand 3 Ligand / Unkown
HY-159459 PROTAC SMARCA2/4 degrader-32 Degrader / Unkown
HY-180931 PROTAC A515 Degrader / Unkown
HY-159458 PROTAC SMARCA2/4 degrader-7 Degrader / Unkown
HY-159453 PROTAC SMARCA2/4 degrader-2 Degrader / Unkown
HY-153425 PROTAC SMARCA2/4 degrader-41 Degrader / Unkown
HY-161885 SMARCA2/4-IN-4 Inhibitor / Unkown
HY-162814 SMARCA2/4-ligand-3 Ligand / Unkown
HY-159457 PROTAC SMARCA2/4 degrader-6 Degrader / Unkown
HY-159454 PROTAC SMARCA2/4 degrader-3 Degrader / Unkown
HY-168230 SMARCA2 ligand-9 Ligand / Unkown
HY-163949 SMARCA2/4-IN-3 Inhibitor / Unkown
HY-170349 SMARCA2 ligand-11 Ligand / Unkown
HY-180960 NEP202 Degrader / Unkown
HY-171765 SMARCA2/4-ligand-6 Ligand / Unkown
HY-176871 PROTAC SMARCA2 degrader-35 Degrader / Unkown
HY-168248 BRM/BRG1 ligand 2 Ligand / Unkown
HY-170354 SMARCA2/4-ligand-4 Ligand / Unkown
HY-178225 PROTAC SMARCA2/4 degrader-39 Degrader / Unkown
HY-170817 SMI-1074 Inhibitor / Unkown
HY-159461 PROTAC SMARCA2/4 degrader-9 Degrader / Unkown
HY-159472 SMARCA2/4-ligand-1 Inhibitor / Unkown
HY-W539427 BRM/BRG1 ligand 1 Ligand / Unkown
HY-172446 SMARCA2/4-ligand-5 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smarca2 NCBI NCBI:6595