LO-3-62
LO-3-62 is a PROTAC-like SMARCA2/4 degrader with a truncated fumaramide handle. LO-3-62 degrades SMARCA2/4 in cells.
For research use only. We do not sell to patients.
- Formula: C23H22ClN7O3
- Molecular Weight:479.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
LO-3-62 (1-10 μM, 24 h) degrades SMARCA2/4 in MV-4-11 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MV-4-11 cells
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Concentration:1, 10 μM
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Incubation Time:24 h
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Result:Degraded SMARCA2/4 in MV-4-11 cells.
Chemical Information
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Molecular Weight 479.92
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Formula C23H22ClN7O3
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SMILES
O=C(NC1=CC(Cl)=CN=C1)/C=C/C(N2CCN(C3=CC(C4=CC=CC=C4O)=NN=C3N)CC2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LO-3-62 Related Classifications
HY-175186 Related Classifications
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