1. Gene
  2. CDC20 - cell division cycle 20 Gene

CDC20 - cell division cycle 20 Gene

Homo sapiens

Also known as CDC20A; p55CDC; bA276H19.3

Gene ID: 991 | Gene type: protein coding

About CDC20

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:43,358,981-43,363,203 (from NCBI)

This gene has 4 transcripts (splice variants), 220 orthologues and 2 paralogues. Biased expression in testis (RPKM 26.5), bone marrow (RPKM 19.7) and 12 other tissues.

Summary

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]

CDC20 Products(1)

mRNA Protein Name
NM_001255.3 NP_001246.2 cell division cycle protein 20 homolog

CDC20 Protein Structure

WD40

WD40: WD domain, G-beta repeat (302 - 336)

WD40

WD40: WD domain, G-beta repeat (345 - 386)

WD40

WD40: WD domain, G-beta repeat (436 - 470)

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  • 499 a.a.
Protein Preferred Names Protein Names

cell division cycle protein 20 homolog

CDC20 cell division cycle 20 homolog

Related Diseases

Diseases Alias
Mosaic Variegated Aneuploidy Syndrome 1

Mva Syndrome

MVA1

Mosaic Variegated Aneuploidy Syndrome, Type 1

Mosaic Variegated Aneuploidy Syndrome

Congenital Chromosomal Disease

Mosaic Variegated Aneuploidy Syndrome

Warburton-Anyane-Yeboa Syndrome

Mva Syndrome

Mosaic Variegated Aneuplody Microcephaly Syndrome

Warburton Anyane Yeboa Syndrome

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus CDC20 VGNC VGNC:107502
Rattus norvegicus CDC20 RGD RGD:620477
Mus musculus CDC20 MGD MGI:1859866
Bos taurus CDC20 VGNC VGNC:27060
Canis familiaris CDC20 VGNC VGNC:38987