HBF-0079
HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 315702-93-3
- Formula: C12H9N5S
- Molecular Weight:255.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30 μM
Compound: 10
|
Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay
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[PMID: 18774291] |
| Huh-7 | CC50 |
1.1 μM
Compound: HBF-0079
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Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HuH7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
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[PMID: 27793566] |
Chemical Information
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CAS No. 315702-93-3
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Molecular Weight 255.30
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Formula C12H9N5S
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SMILES
C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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