HDAC6-IN-31
HDAC6-IN-31 (compound 8m) is a selective HDAC6 inhibitor, with the IC50 value of 0.026 μM, that significantly inhibits the production and release of pro-inflammatory cytokines. While HDAC6 is critically involved in the activation of inflammasomes, HDAC6-IN-31 has the potential to inhibit NLRP3 inflammasome-driven inflammatory diseases. HDAC6-IN-31 also inhibits glioblastoma cell migration.
For research use only. We do not sell to patients.
- Formula: C15H13FN4O2
- Molecular Weight:300.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HDAC1 3.07 μM (IC50) |
HDAC6 0.026 μM (IC50) |
Chemical Information
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Molecular Weight 300.29
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Formula C15H13FN4O2
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SMILES
FC1=C(NC2=C(C)N=C3N2C=CC=C3)C=CC(C(NO)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)