D44
D44 is a Plasmodium FKBP35 inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC50 values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases.
For research use only. We do not sell to patients.
- CAS No.: 826998-10-1
- Formula: C16H16N4OS
- Molecular Weight:312.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 826998-10-1
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Molecular Weight 312.39
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Formula C16H16N4OS
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SMILES
O=C(CSC1=NC2=CC=CN=C2N1)NC3=CC=CC=C3CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Atack TC, et al. Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35. ACS Med Chem Lett. 2020 Sep 1;11(11):2131-2138. [Content Brief]
[2]. Harikishore A, et al. Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent[J]. Scientific reports, 2013, 3(1): 2501. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D44 Related Classifications
HY-W046346 Related Classifications
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