HSP90i
HSP90i is a HSP90 inhibitor. HSP90i can be used as a drug intermediate to synthesize LYTACs, such as dPDL1-4 (HY-174468).
For research use only. We do not sell to patients.
- CAS No.: 1472616-48-0
- Formula: C22H27N5O3
- Molecular Weight:409.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1472616-48-0
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Molecular Weight 409.48
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Formula C22H27N5O3
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SMILES
CC(C1=C(C=C(C(C2=NN=C(N2C3=CC=C(C=C3)CN4CCNCC4)O)=C1)O)O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zhang D, et al. Extracellular HSP90-Facilitated Degradation of Extracellular and Membrane Proteins by Bifunctional Small Molecules. J Med Chem. 2025 Jun 26;68(12):12641-12657. [Content Brief]
[2]. Rastogi S, et al. An update on the status of HSP90 inhibitors in cancer clinical trials. Cell Stress Chaperones. 2024 Aug;29(4):519-539. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)