Bactobolin C
Bactobolin C is an antibiotic produced by Pseudomonas sp. BMG13A7, which has strong antimicrobial and antitumor activities, can also inhibit antibody production and treat autoimmune encephalomyelitis. However, its undesirable toxicity limits its medicinal application. The unique chemical structure and promising biological activities of Bactobolin C have attracted people's interest in its total synthesis and new active analogs. So far, the structural modification of Bactobolin C has mainly focused on the hydroxyl groups on the amino acid side chains and backbone.
For research use only. We do not sell to patients.
- CAS No.: 74141-69-8
- Formula: C14H20Cl2N2O5
- Molecular Weight:367.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Biological Activity
Description
Chemical Information
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CAS No. 74141-69-8
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Molecular Weight 367.23
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Formula C14H20Cl2N2O5
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SMILES
C[C@@H](N)C(N[C@@H]1[C@@]2([H])C(C(O[C@]1(C)C(Cl)Cl)=O)=C(C[C@H](C2)O)O)=O
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Synonyms
Y 14556
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Initial Source
Streptomyces.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bactobolin C Related Classifications
HY-123558 Related Classifications
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