4-Hydroxy MET
Based on 1 Customer Validation
4-Hydroxy MET (4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine) is a synthetic tryptamine psychoactive substance. 4-Hydroxy MET is a partial 5-HT2A receptor agonist, a serotonin transporter inhibitor and weak norepinephrine transporter inhibitor. 4-Hydroxy MET affects emotional, motoric, and cognitive functions via serotonergic hallucinogenic activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.30%
- CAS 番号: 77872-41-4
- 分子式: C13H18N2O
- 分子量:218.29
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
4-Hydroxy MET (5-100 μM; 60-120 min) incubation of pooled human liver microsomes generates 12 distinct phase I metabolites, with mono-hydroxylation, dihydroxylation, demethylation, deethylation, carboxylic acid formation, and N-oxide formation as key biotransformation pathways[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 77872-41-4
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性状 Solid
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分子量 218.29
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分子式 C13H18N2O
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Color White to light blue
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SMILES
CN(CCC1=CNC2=C1C(O)=CC=C2)CC
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別名
4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (458.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5811 mL | 22.9053 mL | 45.8106 mL | 114.5266 mL |
| 5 mM | 0.9162 mL | 4.5811 mL | 9.1621 mL | 22.9053 mL | |
| 10 mM | 0.4581 mL | 2.2905 mL | 4.5811 mL | 11.4527 mL | |
| 15 mM | 0.3054 mL | 1.5270 mL | 3.0540 mL | 7.6351 mL | |
| 20 mM | 0.2291 mL | 1.1453 mL | 2.2905 mL | 5.7263 mL | |
| 25 mM | 0.1832 mL | 0.9162 mL | 1.8324 mL | 4.5811 mL | |
| 30 mM | 0.1527 mL | 0.7635 mL | 1.5270 mL | 3.8176 mL | |
| 40 mM | 0.1145 mL | 0.5726 mL | 1.1453 mL | 2.8632 mL | |
| 50 mM | 0.0916 mL | 0.4581 mL | 0.9162 mL | 2.2905 mL | |
| 60 mM | 0.0764 mL | 0.3818 mL | 0.7635 mL | 1.9088 mL | |
| 80 mM | 0.0573 mL | 0.2863 mL | 0.5726 mL | 1.4316 mL | |
| 100 mM | 0.0458 mL | 0.2291 mL | 0.4581 mL | 1.1453 mL |
4-Hydroxy MET 関連分類
製品番号: HY-118796
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- 4-Hydroxy MET
- 77872-41-4
- 4-HO-MET
- 4-Hydroxy-N-methyl-N-ethyltryptamine
- 5-HT Receptor
- Serotonin Transporter
- norepinephrine transporter
- human liver microsomes
- phase I metabolites
- dihydroxylation
- N-oxide formation
- deethylation
- 5-HT2A receptor
- demethylation
- serotonin transporter
- mono-hydroxylation
- Inhibitor
- inhibitor
- inhibit