DL-Dopa
Based on 1 Customer Validation
DL-Dopa is a dopamine precursor. It serves as a substrate for Mushroom Tyrosinase, which oxidizes it to dopaquinone, an intermediate in the DOPA-melanin polymerization process, and this reaction can be detected at 475 nm. DL-Dopa also forms synergistic hydrophobic and π-π stacking interactions with cationic surfactants. Its binding to cetylpyridinium chloride (HY-B1464) is stronger and exhibits better thermodynamic stability than its binding to benzalkonium chloride (HY-B2232). DL-Dopa can compensate for dopamine depletion in the brain and is applicable to research related to Parkinson's disease.
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- 純度: 98.58%
- CAS 番号: 63-84-3
- 分子式: C9H11NO4
- 分子量:197.19
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Dopamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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Human Endogenous Metabolite |
DL-Dopa (6.7 mM; 7 min) is oxidized by mushroom tyrosinase to form a colored product at 475 nm, and Kojic acid (HY-W050154) inhibits this oxidation rate in a concentration-dependent manner[1].
DL-Dopa (6.6-6.7 mM; 20 h) can be completely oxidized to Dopaquinone by mushroom tyrosinase; under in vitro conditions, in the presence of Kojic acid, Dopaquinone interacts with Kojic acid to form a yellow product at 335 nm instead of polymerizing into DOPA-melanin[1].
Oxidation of DL-Dopa (6.7 mM; 7 min) catalyzed by mushroom tyrosinase induces oxygen uptake, while Kojic acid inhibits the rate of this oxygen uptake in a concentration-dependent manner.[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 63-84-3
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性状 Solid
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分子量 197.19
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分子式 C9H11NO4
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Color White to off-white
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SMILES
NC(CC1=CC=C(O)C(O)=C1)C(O)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
1 M HCl : ≥ 100 mg/mL (507.13 mM)
H2O : 50 mg/mL (253.56 mM; adjust pH to 1 with 1 M HCl)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
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- Deutsch - DE (393 KB)
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- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / 1 M HCl | 1 mM | 5.0713 mL | 25.3563 mL | 50.7125 mL | 126.7813 mL |
| 5 mM | 1.0143 mL | 5.0713 mL | 10.1425 mL | 25.3563 mL | |
| 10 mM | 0.5071 mL | 2.5356 mL | 5.0713 mL | 12.6781 mL | |
| 15 mM | 0.3381 mL | 1.6904 mL | 3.3808 mL | 8.4521 mL | |
| 20 mM | 0.2536 mL | 1.2678 mL | 2.5356 mL | 6.3391 mL | |
| 25 mM | 0.2029 mL | 1.0143 mL | 2.0285 mL | 5.0713 mL | |
| 30 mM | 0.1690 mL | 0.8452 mL | 1.6904 mL | 4.2260 mL | |
| 40 mM | 0.1268 mL | 0.6339 mL | 1.2678 mL | 3.1695 mL | |
| 50 mM | 0.1014 mL | 0.5071 mL | 1.0143 mL | 2.5356 mL | |
| 60 mM | 0.0845 mL | 0.4226 mL | 0.8452 mL | 2.1130 mL | |
| 80 mM | 0.0634 mL | 0.3170 mL | 0.6339 mL | 1.5848 mL | |
| 100 mM | 0.0507 mL | 0.2536 mL | 0.5071 mL | 1.2678 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
DL-Dopa 関連分類
HY-113404 関連分類
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