Anticancer agent 223
Anticancer agent 223 (Compound V-d) is an anticancer agent that triggers cell death through caspase-dependent and caspase-independent mechanisms. Anticancer agent 223 inhibits tumor spheroid formation and resensitizes cisplatin (HY-17394)-resistant A2780 cells to cisplatin (HY-17394) treatment.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1328150-75-9
- 分子式: C20H19ClN4O
- 分子量:366.84
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
5.68 μM
Compound: V-d
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Antiproliferative activity against human A2780 cells assessed as cell viability incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human A2780 cells assessed as cell viability incubated for 72 hrs by CCK8 assay
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[PMID: 38754563] |
| HK-2 | IC50 |
>50 μM
Compound: V-d
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Cytotoxicity against HK-2 cells
Cytotoxicity against HK-2 cells
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[PMID: 38754563] |
化学情報
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CAS 番号 1328150-75-9
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分子量 366.84
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分子式 C20H19ClN4O
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SMILES
ClC1=CC=C(NC(C2CCN(C3=NC=NC4=C3C=CC=C4)CC2)=O)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Anticancer agent 223 関連分類
HY-161661 関連分類
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