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United States

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製品番号: HY-182907

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Antimalarial agent 60

Antimalarial agent 60 is an antimalarial agent with an IC₅₀ of 116.2 nM against asexual blood-stage parasites of Plasmodium falciparum 3D7. Antimalarial agent 60 can be used in malaria research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₁₈H₁₃F₄N₃O₃
分子量:395.31

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antimalarial agent 60 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Parasite アイソフォーム固有の製品をすべて表示 :

体外実験

Antimalarial agent 60 (Compound 53) (1-10 μM; 72 h) potently inhibits the asexual blood-stage Plasmodium falciparum strain 3D7, with an IC₅₀ of 116.2 nM; meanwhile, this compound exhibits extremely low cytotoxicity against human HepG2 cells, with a CC₅₀ > 20 μM and a selectivity index > 170^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 395.31
分子式 C₁₈H₁₃F₄N₃O₃
SMILES

FC1=C(F)C=C(NC(N(C(CC)C(NC2=CC=C(F)C(F)=C2)=O)C3=O)=O)C3=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Lohawittayanan D, et al. From Hit to Lead: Systematic Optimization of the Quinazolinedione Scaffold as Potent and Noncytotoxic Antimalarial Agents. ACS omega. 2026 Apr 21;11(15):22796-22806. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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