Azidocillin
Based on 1 Customer Validation
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases. Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.05%
- CAS 番号: 17243-38-8
- 分子式: C16H17N5O4S
- 分子量:375.40
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
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β-lactam |
Azidocillin (0.004-16.0, >16.0 μg/mL; 24 h) inhibits the growth of most bacteria isolated from human mandibular osteitis, with mean MIC values ranging from 0.005 to 1.2 μg/mL across bacterial genera, and only a small subset of strains exhibiting MIC values above 2.0 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 17243-38-8
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性状 Solid
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分子量 375.40
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分子式 C16H17N5O4S
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Color White to off-white
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SMILES
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](N=[N+]=[N-])C3=CC=CC=C3)=O)N1C2=O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (266.38 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Bystedt H, et al. Concentration of azidocillin, erythromycin, doxycycline and clindamycin in dental alveolar serum after single oral doses. Int J Oral Surg. 1977;6(2):65-74. [Content Brief]
[2]. Ryrfeldt A, et al. Biliary excretion of ampicillin, azidocillin and benzylpenicillin in the rat. Acta Pharmacol Toxicol (Copenh). 1973;33(3):219-28. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6638 mL | 13.3191 mL | 26.6383 mL | 66.5956 mL |
| 5 mM | 0.5328 mL | 2.6638 mL | 5.3277 mL | 13.3191 mL | |
| 10 mM | 0.2664 mL | 1.3319 mL | 2.6638 mL | 6.6596 mL | |
| 15 mM | 0.1776 mL | 0.8879 mL | 1.7759 mL | 4.4397 mL | |
| 20 mM | 0.1332 mL | 0.6660 mL | 1.3319 mL | 3.3298 mL | |
| 25 mM | 0.1066 mL | 0.5328 mL | 1.0655 mL | 2.6638 mL | |
| 30 mM | 0.0888 mL | 0.4440 mL | 0.8879 mL | 2.2199 mL | |
| 40 mM | 0.0666 mL | 0.3330 mL | 0.6660 mL | 1.6649 mL | |
| 50 mM | 0.0533 mL | 0.2664 mL | 0.5328 mL | 1.3319 mL | |
| 60 mM | 0.0444 mL | 0.2220 mL | 0.4440 mL | 1.1099 mL | |
| 80 mM | 0.0333 mL | 0.1665 mL | 0.3330 mL | 0.8324 mL | |
| 100 mM | 0.0266 mL | 0.1332 mL | 0.2664 mL | 0.6660 mL |
Azidocillin 関連分類
HY-B2091 関連分類
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