BRD4-IN-2
BRD4-IN-2 is a bromodomain BRD4 inhibitor with an IC50 value of 9.9 nM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2679925-55-2
- 分子式: C43H48N8O11
- 分子量:852.89
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
16.9 nM
Compound: 2
|
Protac activity at Halo-tagged CRBN/Nanoluc fused BRD4 in human HEK293 cells using nano-glo as substrate preincubated for 1 hr followed by substrate addition and measured after 3 min by NanoBRET assay
Protac activity at Halo-tagged CRBN/Nanoluc fused BRD4 in human HEK293 cells using nano-glo as substrate preincubated for 1 hr followed by substrate addition and measured after 3 min by NanoBRET assay
|
[PMID: 36170570] |
化学情報
-
CAS 番号 2679925-55-2
-
分子量 852.89
-
分子式 C43H48N8O11
-
SMILES
CNC(N1N=C(C2=C(C[C@@H]1C)C=C(C(OC)=C2)OC)C3=CC=C(C=C3)N4CCN(CC4)C(COCCOCC(NC5=C6C(N(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=O)=O)=O)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BRD4-IN-2 関連分類
HY-141843 関連分類
Powered by Bioz