Cefroxadine
Cefroxadine (CGP 9000) is an orally active cephalosporin antibiotic. Cefroxadine is more effective than cephalexin against Escherichia coli and Klebsiella pneumoniae with MIC values of 3.13 and 1.56 μg/mL respectively with a concentration of 106 μg/mL. Cefroxadine can be used for the research of infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 51762-05-1
- 分子式: C16H19N3O5S
- 分子量:365.40
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Antibiotic アイソフォーム固有の製品をすべて表示
More
生物活性
|
β-lactam |
Cefroxadine (106-108 μg/mL; overnight) shows antibacterial activities against S. aureus, E. coli, S. typhi, S. paratyphi, S. schottmuelleri, K. apneumoniae and P. mirabilis with MIC values of 1.56, 3.31, 1.56, 1.56, 1.56, 1.56 and 6.25 μg/mL respectively with a concentration of 106 μg/mL[1]. Cefroxadine (104-108 μg/mL; overnight) shows antibacterial activities against 100 E. coli strains with MIC50 and MIC75 values of 4.8-11.5 μg/mL and 6-20 μg/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Mice with E. coli ML4707 and K. pneumoniae GN6445 infection[1]
-
Dosage:0-30 mg/kg
-
Administration:Oral gavage; 0-30 mg/kg; 0 and 3 h after infection
-
Result:Showed a better effect than cephalexin in vivo with ED50 values of 21.4 and 10.9 mg/kg for E. coli ML4707 and K. pneumoniae GN6445 in vivo.
化学情報
-
CAS 番号 51762-05-1
-
分子量 365.40
-
分子式 C16H19N3O5S
-
SMILES
OC(C1=C(OC)CS[C@@]([C@@H]2NC([C@@H](C3=CCC=CC3)N)=O)([H])N1C2=O)=O
-
別名
CGP 9000; Oraspor
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Cefroxadine 関連分類
HY-107064 関連分類
Powered by Bioz