Chktide
Chktide is a synthetic peptide substrate applicable for activity assays of Chk1 kinase and cyk/CaMKII. Chktide contains the Ser53 phosphorylation site of Xenopus cyclin B2.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 289652-77-3
- 分子式: C115H198N40O33S
- 分子量:2701.12
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Chktide serves as a standard synthetic substrate for Chk1 serine protein kinase assays and can be used for the quantitative detection of Chk1 catalytic activity[1].
Chktide contains the Ser53 phosphorylation site of Xenopus cyclin B2, and upon phosphorylation, it induces a prophase-like premature phenotype in fibroblasts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 289652-77-3
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分子量 2701.12
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分子式 C115H198N40O33S
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配列
Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg
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シーケンスの短縮
KKKVSRSGLYRSPSMPENLNRPR
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1].
Walker M, et al. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene. 2009 Jun 18;28(24):2314-23.
[Content Brief]
[2]. Stevens I, et al. Identification of cyk, a cyclin B2 kinase, as a novel calcium/calmodulin-dependent protein kinase II and its role during Xenopus laevis oocyte maturation. Experimental cell research. 1999 Nov 01;252(2):303-18. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Chktide 関連分類
HY-P5961 関連分類
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