Cyclic MKEY
Cyclic MKEY is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY also protects against stroke-induced brain injury in mice.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C113H174N28O34S2
- 分子量:2530.87
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
CXCL4-CCL5 heterodimer formation[1]
化学情報
-
分子量 2530.87
-
分子式 C113H174N28O34S2
-
配列
Cys-Lys-Glu-Tyr-Phe-Tyr-Thr-Ser-Ser-Lys-Ser-Ser-Asn-Leu-Ala-Val-Val-Phe-Val-Thr-Arg-Cys (Disulfide bridge:Cys1-Cys22)
-
シーケンスの短縮
CKEYFYTSSKSSNLAVVFVTRC (Disulfide bridge:Cys1-Cys22)
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615. [Content Brief]
[2]. Iida Y, et al. Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):718-26. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)