Exatecan Intermediate 6
Based on 1 Customer Validation
Exatecan Intermediate 6 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 6 can be used to synthesize Antibody-Drug Conjugates (ADCs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.45%
- CAS 番号: 143655-58-7
- 分子式: C13H14FNO2
- 分子量:235.26
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Camptothecins |
Exatecan (DX-8951) is a?DNA?topoisomerase?I?inhibitor.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 143655-58-7
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性状 Solid
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分子量 235.26
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分子式 C13H14FNO2
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Color Off-white to light yellow
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SMILES
CC(NC(C=C(F)C(C)=C1CCC2)=C1C2=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 25 mg/mL (106.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2507 mL | 21.2533 mL | 42.5065 mL | 106.2663 mL |
| 5 mM | 0.8501 mL | 4.2507 mL | 8.5013 mL | 21.2533 mL | |
| 10 mM | 0.4251 mL | 2.1253 mL | 4.2507 mL | 10.6266 mL | |
| 15 mM | 0.2834 mL | 1.4169 mL | 2.8338 mL | 7.0844 mL | |
| 20 mM | 0.2125 mL | 1.0627 mL | 2.1253 mL | 5.3133 mL | |
| 25 mM | 0.1700 mL | 0.8501 mL | 1.7003 mL | 4.2507 mL | |
| 30 mM | 0.1417 mL | 0.7084 mL | 1.4169 mL | 3.5422 mL | |
| 40 mM | 0.1063 mL | 0.5313 mL | 1.0627 mL | 2.6567 mL | |
| 50 mM | 0.0850 mL | 0.4251 mL | 0.8501 mL | 2.1253 mL | |
| 60 mM | 0.0708 mL | 0.3542 mL | 0.7084 mL | 1.7711 mL | |
| 80 mM | 0.0531 mL | 0.2657 mL | 0.5313 mL | 1.3283 mL | |
| 100 mM | 0.0425 mL | 0.2125 mL | 0.4251 mL | 1.0627 mL |
Exatecan Intermediate 6 関連分類
HY-44369 関連分類
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