EZH2-IN-19
EZH2-IN-19 (conpound N40) is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) WT, with the IC50 of 0.32 nM. EZH2-IN-19 plays an important role in cancer research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3026848-13-2
- 分子式: C40H55N7O3
- 分子量:681.91
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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EZH2 WT 0.32 nM (IC50) |
EZH2 Y641F mutant type 0.03 nM (IC50) |
EZH2 Y641N 0.08 nM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| KARPAS-422 | IC50 |
3.52 nM
Compound: N40
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Antiproliferative activity against human KARPAS-422 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 method
Antiproliferative activity against human KARPAS-422 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 method
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[PMID: 38640588] |
化学情報
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CAS 番号 3026848-13-2
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分子量 681.91
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分子式 C40H55N7O3
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SMILES
CCN(C1CCC(CC1)N(C)C)C2=CC(C3=CC=C4C(N(C(N4C5CCN(C)CC5)=O)C)=C3)=CC(C(NCC6=C(C=C(NC6=O)C)C)=O)=C2C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EZH2-IN-19 関連分類
HY-163741 関連分類
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