EZH2-IN-25
EZH2-IN-25 is an EZH2 inhibitor that inhibits the catalytic subunit of PRC2. EZH2-IN-25 can be used for the research of diffuse large B cell lymphoma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2636048-41-2
- 分子式: C25H30ClN7O2
- 分子量:496.00
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
EZH2 |
体外実験
EZH2-IN-25 (example 53) selectively targets EZH2 within the PRC2 pentameric complex, exhibiting a mechanism of inhibition distinct from SAM-competitive inhibitors and EED K27me3-pocket binders[1].
EZH2-IN-25 selectively targets EZH2 in human cell lines, reducing H3K27me3 levels through a mechanism distinct from SAM-competitive and EED K27me3-pocket binders[1].
EZH2-IN-25 selectively targets EZH2 and modulates proliferation of human cancer cell lines that depend on PRC2 activity to maintain cancerous growth[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2636048-41-2
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分子量 496.00
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分子式 C25H30ClN7O2
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SMILES
ClC1=NC=CC2=C1N=C(N[C@@H]3CC[C@H](CC3)CNC4=NC=C([C@H](C)C(NC5COC5)=O)C=N4)C=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EZH2-IN-25 関連分類
HY-188147 関連分類
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