Glidobactin A
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 108351-50-4
- 分子式: C27H44N4O6
- 分子量:520.66
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
33.3 nM
Compound: glidobactin A
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Cytotoxicity against human HCT116 cells assessed as cell viability after 5 days by MTT assay relative to control
Cytotoxicity against human HCT116 cells assessed as cell viability after 5 days by MTT assay relative to control
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[PMID: 22909174] |
| MIA PaCa-2 | IC50 |
0.069 μM
Compound: 1
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Inhibition of 20S proteasome in human MIAPaCa2 cells after 90 mins by fluorescence-based colorimetry
Inhibition of 20S proteasome in human MIAPaCa2 cells after 90 mins by fluorescence-based colorimetry
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[PMID: 23095088] |
| MIA PaCa-2 | IC50 |
7 x 10-3 μM
Compound: 1
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Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 23095088] |
| MIA PaCa-2 | IC50 |
7 nM
Compound: 1
|
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 23095088] |
化学情報
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CAS 番号 108351-50-4
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分子量 520.66
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分子式 C27H44N4O6
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SMILES
CCCCCCC/C=C/C=C/C(N[C@H](C(N[C@@H]1C(N[C@@H](C)/C=C/C(NCC[C@H](O)C1)=O)=O)=O)[C@H](O)C)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)