TB-11
Based on 1 Customer Validation
TB-11 is a Cathepsin D inhibitor, with IC50s of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), 48.8 nM (BACE1), respectively. TB-11 can be used for tumor research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.71%
- CAS 番号: 1415033-93-0
- 分子式: C52H78N8O12
- 分子量:1007.22
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Cathepsin アイソフォーム固有の製品をすべて表示
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生物活性
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Cathepsin D 0.126 nM (IC50) |
Cathepsin E 1.92 nM (IC50) |
BACE1 48.8 nM (IC50) |
化学情報
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CAS 番号 1415033-93-0
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性状 Solid
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分子量 1007.22
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分子式 C52H78N8O12
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Color White to off-white
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SMILES
CC(C)(C)OC(N[C@@H](C(C)C)C(N(C)[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)[C@@H](O)CC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N(C)[C@H](CC2=CC=CC=C2)C(N3[C@@H](CCC3)C(OC)=O)=O)=O)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (99.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9928 mL | 4.9642 mL | 9.9283 mL | 24.8208 mL |
| 5 mM | 0.1986 mL | 0.9928 mL | 1.9857 mL | 4.9642 mL | |
| 10 mM | 0.0993 mL | 0.4964 mL | 0.9928 mL | 2.4821 mL | |
| 15 mM | 0.0662 mL | 0.3309 mL | 0.6619 mL | 1.6547 mL | |
| 20 mM | 0.0496 mL | 0.2482 mL | 0.4964 mL | 1.2410 mL | |
| 25 mM | 0.0397 mL | 0.1986 mL | 0.3971 mL | 0.9928 mL | |
| 30 mM | 0.0331 mL | 0.1655 mL | 0.3309 mL | 0.8274 mL | |
| 40 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.6205 mL | |
| 50 mM | 0.0199 mL | 0.0993 mL | 0.1986 mL | 0.4964 mL | |
| 60 mM | 0.0165 mL | 0.0827 mL | 0.1655 mL | 0.4137 mL | |
| 80 mM | 0.0124 mL | 0.0621 mL | 0.1241 mL | 0.3103 mL |
TB-11 関連分類
HY-164958 関連分類
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